Table 1

Summary of MCK-βAPP mice exhibiting IBM-like pathology in skeletal muscle

PathologyAge, months
0–1010–1515–2020–30
Intracellular Aβ immunoreactivity
 A20/41/32/32/5
 A60/42/31/22/2
Inflammation
 A20/41/33/32/5
 A60/41/31/22/2
Centric nuclei
 A20/40/32/32/5
 A60/40/31/22/2