Table 2

Comparison of the properties of RE and SE in chromaffin cells

PropertyRESE
ActivationLow–moderate physiological stimulationModerate–high physiological stimulation
Rate∼6,000 fF/min∼140 fF/min
Clathrin dependenceNoneRequired
K+ dependenceNoneRequired
Ca2+ dependenceRequiredNone or minimal
Dynamin dependenceDynamin-1 mediatesDynamin-2 mediates