Table 1.

Comparison of adult brain and larval methylomes in queens and workers

% upmethylated DMGs
No. of methylated genesNo. of mCsNo. of DMGsAdult brainLarvae head
Adult brainLarvae headAdult brainLarvae headAdult brainLarvae headQWQW
5,854*6,086*70,000100,0005612,39944561882
  • Q, queen; W, worker.

  • *A small number of Apis genes seem to be methylated only in one tissue (420 in brain and 510 in larvae). However, it was not possible to determine whether these are genuine cases of genes methylated in a tissue-specific manner or artifacts caused by uneven coverage and/or filtration issues.