Table 1.

Clinical characteristics of the patients with malaria

Patient characteristicUncomplicated hospital infections* (n = 40)Severe anemia, Hb < 5 g/dL (n = 47)Cerebral malaria (Blantyre coma score <3) (n = 30)Respiratory distress (n = 18)Hyperparasitemia (>200,000 per μL) (n = 18)Died (n = 9)
Age: mean ± SD, y2.3 ± 1.12.0 ± 0.92.7 ± 1.31.6 ± 0.92.9 ± 1.32.5 ± 1.3
 Minimum/maximum0.51–5.00.58–4.00.62–4.90.61–3.50.51–4.90.79–4.8
Females, %50.646.840.050.038.955.6
Parasitemia median, p/μL36,08513,79041,93028,315248,00041,930
 Percentiles 25 and 7516,275–70,7701,505–72,2055,110–135,4157,580–93,100214,400–313,60024,230–69,510
Temperature median, °C38.538.138.338.139.038.4
 Percentiles 25 and 7538.0–39.737.4–38.837.7–39.237.5–39.138.1–39.437.5–38.5
Hemoglobin: mean ± SD, g/dL7.6 ± 1.73.9 ± 0.76.5 ± 1.95.4 ± 2.37.4 ± 2.46.5 ± 1.7
 Minimum/maximum5.1–11.81.7–4.93.4–10.51.7–10.03.4–11.94.8–9.5
Mean coma score4.94.41.32.852.1
 Percentiles 25 and 755–55–50–21–53–51–3
 Minimum/maximum3–50–50–20–52–50–5
P-lactate: mean ± SD, mM3.8 ± 1.64.4 ± 2.54.9 ± 3.96.9 ± 4.65.1 ± 1.95.7 ± 4.4
Mortality, %02.120.028.05.6100
  • *Patients requiring admission to Korogwe District Hospital without fulfilling any of the criteria for classification as complicated malaria.

  • The patient who died with hyperparasitemia did not have any other symptoms of severe malaria (Blantyre coma score = 5, hemoglobin level = 8.5 g/dL, no symptoms of respiratory distress, plasma lactate = 4.1 mmol/L).