Table 1.

Genotype distribution of embryos and pups from intercrosses of Sec23bgt/+ mice

Sec23b genotype
Background+/+ (%)gt/+ (%)gt/gt (%)P value
E18.5 (n = 154), C57BL/6J45 (29.2)78 (50.7)31 (20.1)>0.2
E16.5 (n = 81), C57BL/6J19 (23.5)47 (58)15 (18.5)>0.2
E15.5 (n = 142), C57BL/6J33 (23.2)75 (52.8)34 (24)>0.7
E14.5 (n = 103), C57BL/6J28 (27.2)59 (57.3)16 (15.5)>0.08
E13.5 (n = 64), C57BL/6J15 (23.4)34 (53.1)15 (23.4)>0.8
Weaning (n = 57), C57BL/6J18390
Weaning (n = 44), 129/SvImJ13310
  • Mice were backcrossed at least eight generations into the C57BL/6J or 129/SvImJ background.