Table 1.

Half maximal inhibitory concentrations (IC50) for Hh pathway (in μM)

SA1SA2SA3SA4SA5SA6SA7SA8SA9SA10CA1Cyclopamine
Shh-LIGHT2 cells (Gli-luciferase)3.1121.20.9259.25.818195>250.9
Ptch1−/− fibroblast (β-gal)3.89.9201.3257.33.219111>250.15