Table 3.

Fragmented AvG transport across full-thickness pig skin (n = 3)

Graphic
  • Avs were fragmented as described using weak-base and strong-base hydrolysis and then labeled with 125I. The average ± SD is reported. Both weak-base and strong-base fragments were significantly less permeable than AvG, despite their lower molecular weight (AvG vs. weak-base fragment, P < 0.1; AvG vs. strong-base fragment, P < 0.05). NA, not applicable.

  • *Statistically significant values.