Table 1.

Numbers and mutational spectra of base substitutions according to genetic background

SubstitutionAncestormutTmutT mutY-EmutT mutY-L
A:T→T:A5 (1, 4, 0)000
A:T→C:G8 (1, 5, 2)412 (48, 307, 57)233 (32, 159, 42)292 (41, 205, 46)
A:T→G:C6 (0, 2, 4)01 (0, 1, 0)1 (0, 1, 0)
C:G→T:A15 (0, 13, 2)02 (1, 1, 0)2 (1, 1, 0)
C:G→G:C2 (0, 2, 0)000
C:G→A:T5 (0, 3, 2)2 (0, 2, 0)38 (13, 18, 7)24 (6, 15, 3)
Total41 (2, 29, 10)414 (48, 309, 57)274 (46, 179, 49)319 (48, 222, 49)
  • Point mutations along all branches in the phylogenetic tree for each background (i.e., branches of the same color in Fig. 1A). Numbers in parentheses show the separate counts for synonymous, nonsynonymous, and noncoding mutations, respectively.