Table 1.

dre-1 is required for tail-spike cell death

GenotypeTail-spike cell survival, %
Wild-type0 ± 0
dre-1(ns39)79 ± 3
dre-1(dh99)12 ± 3
dre-1(dh279)2 ± 1
dre-1(ns39)/+0 ± 0
dre-1(dh99)/+0 ± 0
dre-1(ns39)/dre-1(dh99)25 ± 4
dre-1 synergizes with core apoptotic genes
ced-3(n2427)0 ± 0
ced-3(n2427); dre-1(dh99)46 ± 4
ced-4(n3158)74 ± 4
ced-4(n3158); dre-1(dh99)91 ± 3
ced-9(n1950)3 ± 3
ced-9(n1950); dre-1(dh99)59 ± 4
ced-9 is required for dre-1 function
egl-1(n1084n3082)30 ± 6
egl-1(n1084n3082) dre-1(dh99)85 ± 4
egl-1(n1084n3082) dre-1(ns39)94 ± 2
ced-9(n2812); ced-3(n2427)0 ± 0
ced-3(n2427); dre-1(ns39)98 ± 1
ced-9(n2812); ced-3(n2427); dre-1(ns39)20 ± 4
  • Strains contain nsIs25; n >100; error: SEM.