Table 1.

Antibody titers and in vitro growth inhibition

TestI-7C-1Δ[(C-1) − (I-7)]P value
Antibody titer, AU
 CSP0.91 (0; 2.15)24.3 (15.2; 48.5)24.3 (10.8; 47.3)0.006
 AMA-10.12 (0.08; 0.17)0.11 (0.09; 0.17)0.00 (−0.03; 0.01)0.35
 GLURP1.23 (1.01; 2.39)1.06 (0.90; 3.39)−0.13 (−0.35; 0.14)0.46
Growth inhibition, %−3.3 (−7.1; −1.1)−8.6 (−10.0; −5.46)−4.4 (−6.0; 1.8)0.03
  • Antibody titers against CSP, AMA-1, and GLURP and in vitro growth inhibitory activity of isolated IgG in all CPS-immunized subjects, before immunization (I-7) and on the day before challenge (C-1). Data are expressed as median (25; 75 percentile). Differences between time points were tested using a paired t test. AU, arbitrary units.