Table 1.

Variants in NFκB regions have strong effects in particular diseases

Broad phenotypeNFκB mean LRMean LRt test PWilcox P
Rheumatoid arthritis0.36790.30540.01180.0013
Systemic lupus erythematosus0.42760.35870.04100.0010
  • For these diseases, the mean likelihood ratio (LR) for variants in NFκB regions is higher than the average LR for variants associated with the disease.