Table 1.

Rat thigh muscle metabolic parameters

ControlHemorrhageSNO-Hb–depletedSNO-Hb–repleted
ATP5.6 ± 0.74.8 ± 0.44.9 ± 0.94.9 ± 0.7
ADP0.4 ± 0.10.4 ± 0.10.4 ± 0.10.6 ± 0.2*
CrP17 ± 324 ± 6*20 ± 725 ± 2*
Cr11 ± 310 ± 315 ± 312 ± 2
Pyr0.06 ± 0.020.07 ± 0.020.05 ± 0.010.05 ± 0.01
L2.5 ± 0.83.3 ± 1.54.3 ± 2.6*2.6 ± 1.4
L/Pyr39 ± 847 ± 2287 ± 65*51 ± 33
CrP+Cr30 ± 535 ± 837 ± 7*38 ± 2*
  • Muscle metabolic markers under control (n = 7), hemorrhage (n = 9), and transfusion conditions (n = 10 for both). Values followed by an asterisk (*) indicate a significant difference from control values (P < 0.05). ADP, adenosine diphosphate; ATP, adenosine triphosphate; Cr, creatine; CrP, creatine phosphate; L, lactate; L/Pry, lactate/pyruvate ratio; Pyr, pyruvate.