Table 4.

Association of hTERT common alleles/genotypes with exceptional longevity

Nature of variationControls (n = 49)Centenarians (n = 73)P value
Allele, %
TERTExon 1IVS1–187 T > CC36.742.50.3717
Exon 2973 G > A (A 305 A)A30.634.90.4834
Exon 143097 C > T (H 1013 H)T8.121.90.0049
Exon 16IVS16+99 C > TT11.216.40.2556
TERCIVS+63 T > CC18.518.80.9402
Genotype, %
TERTExon 1IVS1–187 T > CTT40.831.50.4494
CT44.952.1
CC14.316.4
Exon 2973 G > A (A 305 A)GG53.143.80.5313
GA32.742.5
AA14.313.7
Exon 143097 C > T (H 1013 H)CC85.763.90.035
CT12.226.8
TT28.5
Exon 16IVS16+99 C > TCC81.668.50.0972
CT14.330.1
TT4.11.4
TERCIVS+63 T > CTT64.466.20.5653
CT34.229.9
CC1.43.9
  • Adjusted for age and gender.