Table 4.

Nine strains with normal sensitivity to heat shock (30–50 °C) that develop significant sensitivity* after pretreatment at 37 °C

ORFNameDescriptionCalculated death rate for the 30 –50 °C experimentCalculated death rate for the 37 –50 °C experiment
YMR126CDLT1Protein of unknown function, mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA)0.47−6.11
YDL020CRPN4Transcription factor that stimulates expression of proteasome genes, transcriptionally regulated by various stress responses2.44−4.14
YIL090WICE2Integral ER membrane protein with type-III transmembrane domains; required for maintenance of ER zinc homeostasis−0.54−4.97
YNL122CYNL122CPutative protein of unknown function0.64−3.79
YER056CFCY2Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation−1.55−5.76
YLR328WNMA1Nicotinic acid mononucleotide adenylyltransferase−0.14−4.31
YIL071CPCI8Possible shared subunit of Cop9 signalosome (CSN) and eIF3−2.51−5.69
YOR328WPDR10ATP-binding cassette (ABC) transporter, multidrug transporter involved in the pleiotropic drug resistance network−1.76−4.81
YPL026CSKS1Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway−0.57−3.59