Table 2.

Summary of transposon excision

Cell lineClones analyzedSingle excisionBiallelic excision without reintegration, no. of clones (frequency)Biallelic excision with reintegration, no. of clones (frequency)
T2-4640 (0%)2 (33.3%)
T1-61162 (18%)2 (18%)
Mean frequency9%25.7%
  • T1, targeting clone used L540long-R560 TALEN pair; T2, targeting clone used L538-R557 TALEN pair.