Table 1.

Boltzmann fit parameters for Shaker and KCNQ channel family GV and steady-state inactivation (SSI) curves

ChannelnV50, mVs, mV
GV
 NvShab7−13.4 ± 1.412.8 ± 0.6
 MmKv2.18−1.0 ± 1.614.3 ± 0.4
 NvShaw16−10.6 ± 5.022.1 ± 1.0
 NvShaw1 + R1875.0 ± 1.827.2 ± 1.1
 NvShaw1 + R2 (first, fraction 0.09 ± 0.02)910.9 ± 0.56.6 ± 0.6
 NvShaw1 + R2 (second)982.1 ± 1.817.6 ± 0.2
 NvShal11118.2 ± 1.215.3 ± 0.6
 NvShal1 + R18−11.2 ± 1.714.6 ± 0.4
 NvShal1 + R212−12.7 ± 1.516.2 ± 0.3
 NvShal1 + R37−3.0 ± 2.215.2 ± 0.6
 NvKCNQ10−36.6 ± 1.68.6 ± 0.2
 HsKCNQ2/314−13.6 ± 1.520.6 ± 0.6
SSI
 NvShab7−34.9 ± 0.55.1 ± 0.2
 MmKv2.17−8.8 ± 0.78.6 ± 0.5
 NvShal19−33.1 ± 0.86.9 ± 0.3
 NvShal1 + R16−20.0 ± 0.811.6 ± 0.7
 NvShal1 + R28−71.7 ± 1.27.8 ± 0.1
 NvShal1 + R39−63.6 ± 1.313.1 ± 0.3
  • n, number of samples; V50, half-maximal activation voltage; s, slope factor.