Table 3.

DDH inhibition by glycerol in MCPs purified from different pore mutants

Type of purified MCPIC50 of glycerol, mM
Wild-type (LT2)291.7 ± 2.2
PduA-S40L1,560 ± 50.1
PduA-S40GSG1,410 ± 35.9
PduA-S40H55.3 ± 1.7
Purified DDH1.2 ± 0.1