Table 1.

Tumor characteristics and the detection of CSF-tDNA

PatientDiagnosisTumor gradeTumor locationLocation of CSF samplingTumor abutting CSF spaceCSF-tDNA
CGLI 02GliomaWHO II, diffuse astrocytomaT11 spinal cordSpinal subarachnoid spaceYesNot detected
CGLI 03Anaplastic astrocytomaWHO III, anaplastic astrocytomaPonsBasal cisternYesPositive
CGLI 06Pilocytic astrocytomaWHO I, pilocytic astrocytomaCerebellar vermisBasal cisternYesPositive
CGLI 11Spinal ependymomaWHO II, ependymomaC7-T3 spinal cordSpinal subarachnoid spaceYesPositive
CGLI 12Intracranial ependymomaWHO II, ependymomaFourth ventricleBasal cisternYesPositive
CGLI 13Myxopapillary ependymomaWHO I, myxopapillary ependymomaL2-3 spinal cordSpinal subarachnoid spaceNAPositive
CGLI 14Intramedullary spinal cord lesionLow-grade neoplasmT7-9 spinal cordSpinal subarachnoid spaceYesPositive
CGLI 15Spinal ependymomaWHO II, ependymomaC3-4 spinal cordSpinal subarachnoid spaceNoNot detected
CGLI 20MedulloblastomaWHO IV, medulloblastomaFourth ventricleBasal cisternYesPositive
CGLI 22Pilocytic astrocytomaWHO I, pilocytic astrocytomaCerebellar hemisphereBasal cisternNoNot detected
CGLI 25Myxopapillary ependymomaWHO I, myxopapillary ependymomaL2-3 spinal cordSpinal subarachnoid spaceYesPositive
CGLI 26Intramedullary spinal cord tumorWHO II, infiltrating astrocytoma with oligodendroglial featuresC3-6 spinal cordSpinal subarachnoid spaceYesPositive
CGLI 28Anaplastic astrocytomaWHO III, anaplastic astrocytomaRight frontal/butterflyVentricleYesPositive
CGLI 29GlioblastomaWHO IV, glioblastomaC4-6 spinal cordSpinal subarachnoid spaceYesPositive
CGLI 31GlioblastomaWHO IV, glioblastomaRight frontal/butterflyVentricleYesPositive
CGLI 35GlioblastomaWHO IV, glioblastomaRight temporalVentricleYesPositive
CGLI 36Spinal cord glioblastomaWHO IV, glioblastomaT10-L1 spinal cordSpinal subarachnoid spaceYesPositive
CGLI 39Intramedullary spinal cord tumorWHO II, low-grade glioma likely ependymomaC2-3 spinal cordSpinal subarachnoid spaceNoNot detected
CGLI 40MedulloblastomaWHO IV, medulloblastomaFourth ventricleBasal cisternYesPositive
CGLI 41GlioblastomaWHO IV, glioblastomaCerebellar hemisphereBasal cisternYesPositive
CGLI 42Spinal ependymomaWHO II, ependymomaT1-7 spinal cordSpinal subarachnoid spaceNAPositive
CGLI 43Low-grade gliomaWHO II, low-grade gliomaT10 spinal cordSpinal subarachnoid spaceYesNot detected
CGLI 44Pilocytic astrocytomaWHO I, pilocytic astrocytomaCerebellar vermisBasal cisternNoNot detected
CGLI 47GlioblastomaWHO IV, glioblastomaRight temporalVentricleYesPositive
CGLI 48GlioblastomaWHO IV, glioblastomaLeft temporalVentricleYesPositive
CGLI 50GlioblastomaWHO IV, glioblastomaRight temporalVentricleYesPositive
CGLI 51GlioblastomaWHO IV, glioblastomaRight frontalVentricleYesPositive
CGLI 55Brainstem glioblastomaWHO IV, glioblastomaMidbrainBasal cisternYesPositive
CGLI 56MedulloblastomaWHO IV, medulloblastomaFourth ventricleBasal cisternYesPositive
CGLI 58Diffuse astrocytomaWHO II, diffuse astrocytomaT2-4 spinal cordSpinal subarachnoid spaceYesNot detected
CGLI 60MedulloblastomaWHO IV, medulloblastomaFourth ventricleBasal cisternYesPositive
CGLI 61Pilocytic astrocytomaWHO I, pilocytic astrocytomaCerebellar vermisBasal cisternYesNot detected
CGLI 63MedulloblastomaWHO IV, medulloblastomaCerebellumBasal cisternNoNot detected
CGLI 101GlioblastomaWHO IV, glioblastomaCerebellar vermisBasal cisternYesPositive
CGLI 254MedulloblastomaWHO IV, medulloblastomaFourth ventricleBasal cisternYesPositive
  • NA, not available.