Table S3.

Complete blood count results for 24-mo-old vehicle-treated (Old Veh) and 24-mo-old JAK inhibitor-treated (Old INCB) mice

Blood parameterOld VehOld INCBP value
WBC6.9 ± 0.85.8 ± 1.00.391
LYM5.3 ± 0.74.4 ± 0.70.386
MON0.46 ± 0.120.53 ± 0.140.412
NEU1.2 ± 0.31.0 ± 0.20.694
LYM%76.5 ± 2.376.7 ± 1.70.946
MON%6.9 ± 1.45.6 ± 0.60.426
NEU%16.6 ± 317.7 ± 1.40.747
RBC9.1 ± 0.58.8 ± 0.40.702
HGB13.3 ± 0.712.9 ± 0.50.626
HCT%38.6 ± 1.937.3 ± 1.40.569
MCV42.7 ± 0.742.3 ± 0.90.709
MCH14.8 ± 0.514.7 ± 0.30.862
MCHC34.6 ± 0.734.6 ± 0.40.959
RDWc%20.6 ± 0.320.2 ± 0.50.436
RDWs34.8 ± 1.133.9 ± 1.50.632
PLT523 ± 145244 ± 720.112
MPV7.5 ± 0.17.7 ± 0.40.607
PCT%0.39 ± 0.10.40 ± 0.050.109
PDWc%32.6 ± 0.932.1 ± 0.90.716
PDWs9.3 ± 0.79.0 ± 0.70.763
  • All values are shown as mean ± SEM; n = 7. HCT, hematocrit; HGB, hemoglobin (in grams per deciliter); LYM, lymphocyte count (109/L); LYM%, lymphocyte percentage; MCH, mean corpuscular hemoglobin (in picograms); MCHC, mean corpuscular hemoglobin concentration (in grams per deciliter); MCV, mean corpuscular volume (in femoliters); MON, monocyte count (109/L);MON%, monocyte percentage; MPV, mean platelet volume (in femoliters); NEU, neutrophil count (109/L); NEU%, neutrophil percentage; PCT%, plateletcrit percentage; PDWc, platelet distribution width, coefficient of variation %; PDWs, platelet distribution width (in femoliters); PLT, platelet count (109/L); RBC, red blood cell count (1012/L); RDWc, red cell distribution width, coefficient of variation %; RDWs, red cell distribution width (in femoliters); WBC, total white blood cell count (109/L).