Table 2.

Clinicopathological correlation of TKT overexpression in human HCC

Clinicopathological featuresStatusNumber of casesMean of −∆∆Ct, T-NTP value
GenderMale791.260.523
Female220.98
Venous invasionAbsent430.610.002**
Present551.69
Tumor encapsulationAbsent641.510.025*
Present330.69
Tumor microsatellite formationAbsent480.770.013*
Present491.62
Hepatitis B surface antigenAbsent231.630.129
Present711.00
Direct liver invasionAbsent540.970.130
Present341.50
Cellular differentiation by Edmondson gradingI and II461.080.529
III and IV511.30
Tumor size≤5 cm360.700.028*
>5 cm611.49
CirrhosisAbsent461.350.483
Present521.10
Tumor stageI and II351.730.066
III and IV631.77
  • mRNA expression of TKT in paired HCC tumor and NT samples was measured by qRT-PCR. *P < 0.05, **P < 0.01, Student’s t test.