Table 2.

Retinal gene identities of top responders after systemic Roxadustat or DMOG (fold-change vs. PBS)

SymbolAlternative gene nameRoxadustatDMOG
S100a9S100 calcium binding protein A99.1
Dio3Deiodinase, iodothyronine, type III7.4
Slc16a3Solute carrier family 16 member 36.8
Ppp1r3gProtein phosphatase 1 subunit 3G6.5
Ak4Adenylate kinase 45.3
Ca9Carbonic anhydrase IX4.0
GrhprGlyoxylate/hydroxypyruvate reductase3.8
Upk3bUroplakin 3B3.72.3
Csn3Casein kappa3.5
Pdk1Pyruvate dehydrogenase kinase2.9
PfklPhosphofructokinase, liver2.8
Prss56Serine protease 562.52.6
Hist1h4bHistone cluster 1, H2b2.5
Hist1h2anHistone cluster 1, H2an2.4
Tnfsf9Tumor necrosis factor member 92.3
Bnip3BCL2/adenovirus E1B protein 32.3
Ascl1Achaete-scute complex homolog 12.2
MyocdMyocardin2.2
Hist1h4aHistone cluster 1, H4a2.2
Tpi1Triosephosphate isomerase 12.1
Stc2Stanniocalcin 22.1
Ankrd2Ankyrin repeat domain 22.1
Smtnl2Smoothelin-like 22.1
MifMacrophage migration inhibitory factor2.1
Hist1h3dHistone cluster 1, H3d2.12.1
Pgk1Phosphoglycerate kinase 12.0
H2-Ab1Major histocompatibility complex II2.0
Selenbp2Selenium binding protein 22.0
Ripply3Ripply3 homolog2.0
Ankrd37Ankyrin repeat domain 372.0
Hist1h2aiHistone cluster 1, H2ai2.0