Table S6.

Description of cohorts

Descriptive variableHRS0HRS1HRS2HRS3
Included in the study sample?NoYesYesYes
Year of birth1924–19301931–19411942–19471948–1953
Females
N (genotyped and not genotyped)1,7363,5051,5281,381
Age asked no. of children, first–99th percentiles, y65–7755–7349–6645–62
Age when genotyped (in 2006–2008), y76–8465–7759–6653–60
Fraction survived to 20080.690.820.900.96
Fraction asked to be genotyped (in 2006–2008)0.590.700.740.73
Fraction consented to be genotyped (in 2006–2008)0.510.610.620.63
Fraction in sample of genotyped individuals0.440.520.530.55
Males
N (genotyped plus not genotyped)1,5623,2311,0681,137
Age asked no. of children, first–99th percentiles, y66–8055–7550–6850–62
Age when genotyped (in 2006–2008), y76–8465–7759–6653–60
Fraction survived to 20080.600.760.860.97
Fraction asked to be genotyped (in 2006–2008)0.520.630.650.70
Fraction consented to be genotyped (in 2006–2008)0.470.540.550.58
Fraction in sample of genotyped individuals0.390.460.470.50
  • For each cohort, I include all individuals of European ancestry born in the cohort's years of birth, who were enrolled in the HRS and asked the number of children they ever gave birth to or fathered in 2008 or earlier, and who were at least 45 y old when asked the number of children they ever gave birth to (for females) or at least 50 y old when asked the number of children they ever fathered (for males). “Fraction in sample of genotyped individuals” indicates the fraction of individuals who are in the sample of unrelated genotyped individuals who passed the quality control filters described in SI Materials and Methods (the sample used in the analyses with the genotyped individuals). The HRS0 cohort is not included in the study sample because of the high mortality among its members by 2008 (the last year when individuals were genotyped) and because of evidence of selection bias for the genotyped individuals in that cohort. The main results are robust to the inclusion of that cohort.