Table 5.

Metabolic similarities and contrasts between CFS and Dauer, cell danger and metabolic syndrome

Plasma metabolitesCFSDauerCDR (7)Metabolic syndrome
SphingolipidsDecreased (M + F)*Decreased (62)Increased (63)Increased (64)
GlycosphingolipidsDecreased (M + F)Decreased (62)Increased (63)Increased (65)
Phospholipids, most speciesDecreased (M + F)Decreased (66)Increased (67)Increased (68)
PC(18:1/22:6)—Oleoyl/DHA phospholipidsIncreased (M + F)No dataDecreased (67)Decreased (13)
Cholesterol, sterol synthesisDecreased (M + F)Decreased (69)Increased (70)Increased (71)
PurinesDecreased (M + F)Decreased (72)Increased (73)Increased (74)
Uric acidDecreased (M)N/AIncreased (75)Increased (76)
P5C/ArgIncreased (M + F)No dataDecreased (77)No data
FAD/RiboflavinDecreased (M + F)Decreased (72)Increased (20)No data
  • * F, females only; M, males only; M + F, males and females.

  • N/A, the end products of purine metabolism in worms are glyoxylate and ammonia, not uric acid.