Table S1.

Dynamic regulation of AtDAO1 and GH3 modulates auxin homeostasis

ParameterSet 1: dao1-1 only differs in rate of IAA oxidationSet 2: dao1-1 differs in rates of IAA oxidation, biosynthesis, and conjugationSet 3: dao1-1 only differs in rate of IAA oxidation, but AtDAO1 and GH3 are auxin-inducible
λ111
λ*11.361.36
d10.01550.5224
d1*00
ga0.33240.0012
ga*0.33240.4382
gg0.63990.0018
gg*0.63990.3594
uf0.1311.7864515.7453
ur0.00420.042813.5992
μa1.45810.01230.0185
μg3.01290.04070.0174
μu0.00010.00060.0002
d20.01590.38560.3379
μp0.05630.00120.0097
μx0.00590.18600.1893
d^11.8471
d^1*0
g^a83.5023
g^a*83.5023
g^g19.5837
g^g*19.5837
nd1
kd1
ηd0.005
ng9.0
kg2.3227
ηg0.01
  • Representative fitted parameter sets for the various models for auxin homeostasis. Set 1: simple AtDAO1 KO model (d1*=0 in dao1-1 simulation) using Eqs. S1aS1f. Parameters with superscript * are for the dao1-1 case. Here, we assume ga=ga*, gg=gg*, and λ=λ*. Set 2: fitted parameter set using Eqs. S1aS1f for dao1-1 simulation with d1*=0, λ*=1.36, and ga* and gg* free to vary within the default constraints. Set 3: Representative fitted parameter set for model with inducible AtDAO1 and GH3 used to produce Fig. 3 and as the basis for the parameterization of the multicellular model. Parameter constraints are in SI Text.