Table S1.

DNA thermal stabilization analysis of compounds 1–4 on TS match and mismatch sequence

Polyamide5′-GACT TGGTCA TACA -3′5′-GACT TGTTCA TACA -3′
Tm/°CΔTm/°CTm/°CΔTm/°C
56.4 ± 0.752.9 ± 0.5
171.3 ± 0.814.953 ± 0.80.1
266.6 ± 0.710.255.9 ± 0.23.0
371.1 ± 0.814.754.2 ± 1.01.3
471.8 ± 0.915.453.1 ± 0.30.2
  • The compound binding site is indicated in bold font.