Table 1.

Effects of β2ARKO on chemokine receptor expression

Chemokine receptorWT BMTβ2ARKO BMT
CCR11.00 ± 0.201.06 ± 0.13
CCR21.00 ± 0.210.27 ± 0.07*
CCR51.00 ± 0.161.32 ± 0.18
CXCR11.00 ± 0.541.71 ± 0.56
CXCR21.00 ± 0.511.63 ± 0.62
CXCR41.00 ± 0.060.32 ± 0.02*
CXCR71.00 ± 0.030.90 ± 0.04
CXC3CR11.00 ± 0.121.09 ± 0.14
CD451.00 ± 0.220.90 ± 0.30
  • RT-qPCR analysis of changes in expression of chemokine receptor transcripts in reconstituted WT or β2ARKO BM from transplanted mice. n = 4–8.

  • * P < 0.001 vs. WT BMT, two-tailed unpaired t test.