Table S5.

Statistical comparison of the percent of directed vaccine effect for anatomical locations indicated in Fig. 3B

DayMean diff.95% CI of diff.Significant
Nasopharynx
 13024.02–35.98Yes
 23125.02–36.98Yes
 35650.02–61.98Yes
 49690.02–102Yes
 58478.02–89.98Yes
 68377.02–88.98Yes
 76155.02–66.98Yes
 89488.02–99.98Yes
 910498.02–110Yes
 104337.02–48.98Yes
 117569.02–80.98Yes
 127165.02–76.98Yes
 136054.02–65.98Yes
 146660.02–71.98Yes
Nasopharynx lavage
 19892.02–104Yes
 2135129–141Yes
 36458.02–69.98Yes
 44337.02–48.98Yes
 59690.02–102Yes
 6112106–118Yes
 710094.02–106Yes
 88377.02–88.98Yes
 94034.02–45.98Yes
 102519.02–30.98Yes
 116155.02–66.98Yes
 125044.02–55.98Yes
 133327.02–38.98Yes
 144135.02–46.98Yes
Lung
 1−22−27.98 to −16.02Yes
 23327.02–38.98Yes
 35246.02–57.98Yes
 43731.02–42.98Yes
 52620.02–31.98Yes
 65953.02–64.98Yes
 75448.02–59.98Yes
 85953.02–64.98Yes
 95852.02–63.98Yes
 104943.02–54.98Yes
 114741.02–52.98Yes
 125448.02–59.98Yes
 137771.02–82.98Yes
 146559.02–70.98Yes
  • CI, confidence interval; Mean Diff., mean difference between planktonic and biofilm-released values. All adjusted P values <0.0001.