Table S6.

Cardiac mRNA levels and serum concentration levels of cytokines/growth factors in 72-h post-I/R WT and Mcpt4−/− mice

Cytokines/growth factorsCardiac mRNA (relative expression) at 72 h after I/RSerum cytokine/growth factor at 72 h after I/R, pg/mL
WTMcpt4−/−P valueWTMcpt4−/−P value
TNFα1.0 ± 0.231.22 ± 0.15(0.45)100 ± 1195 ± 12(0.81)
TGFβ1.0 ± 0.130.49 ± 0.023(0.0091)910 ± 140740 ± 160(0.43)
IL1β1.0 ± 0.191.74 ± 0.47(0.18)110 ± 1180 ± 16(0.12)
MCP11.0 ± 0.230.81 ± 0.14(0.5)1,000 ± 63900 ± 110(0.43)
n per group4466
  • Values are mean ± SEM mRNA transcripts were determined by quantitative real-time RT-PCR, and expression was normalized against 18S rRNA. mRNA values are expressed relative to those in 72-h post-I/R WT hearts. Values were compared by using unpaired Student’s t test.