Table S1.

Effect of other drugs on proliferation of astrocytes (primary screening)

% effect
Drugs and bioactive compoundsWild typeCcm3−/−
Antineoplastic
 Salinomycin45.0166.17
 Vinblastine sulfate30.2065.57
 Mitoxanthrone hydrochloride33.9062.19
39.4057.83
 Dasatinib45.3057.39
 Trichlormethine hydrochloride43.4953
Antifungal
 Phenylmercuric acetate26.2886.1
43.6183.74
 Thiram−17.2074.14
−16.7968.35
 Ciclopirox olamine15.2353.85
Antibacterial
 Proflavine hemisulfate21.0973.47
 Pyrithione zinc15.5765.91
−3.7360.65
Anthelmintic
 Tetramizole hydrochloride19.5165.85
Others
 Bay 11-708254.6877.72
 Methylene blue10.0576.72
 Patulin7.5972.29
  • Percent (%) effect of other drugs retained after the hit-pick phase on the proliferation of wild-type and Ccm3−/− primary astrocytes.