Table 2.

TAP amber and red flag regions, as defined by the entire set of 242 CSTs

MetricAmber flag regionRed flag region
Total CDR length54 ≤ L ≤ 60L > 60
PSH, CDR vicinity83.84 ≤ PSH ≤ 100.71PSH < 83.84
156.20 ≤ PSH ≤ 173.85PSH > 173.85
PPC, CDR vicinity1.25 ≤ PPC ≤ 3.16PPC > 3.16
PNC, CDR vicinity1.84 ≤ PNC ≤ 3.50PNC > 3.50
SFvCSP-20.40 ≤ SFvCSP ≤ -6.30SFvCSP < -20.40
  • PSH score is calculated with the Kyte and Doolittle (31) hydrophobicity scale. L, length.