Table 1.

Nonsynonymous mutations in Mpi

Exon pos.AA pos.Ancestral/DerivedNotation (Type)
4315Alagcc/ProcccA15P (C)
553185Cystgt/ArgcgtC185R (E)
727243Phettc/LeuctcF243L (C)
755252Thracc/IsoatcT252I (R)
815272Glygga/GlugaaG272E (E)
956319Seragc/ThraccS319T (C)
1040/1041347Thracg/aca/MetatgT347M (R)
1168390Glucag/LysaagQ390K* (E)
1174392Alagcg/ThracgA392T (R)
  • Exon and protein positions are listed, as well as their products (ancestral and derived states) and notations. The fast/slow mutation is indicated with an asterisk. C, conservative; E, charge changing; R, radical.