New Research In

antiviral

Open Access
Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Yu-Pu Juang, Hsiu-Hua Ma, Ying-Ta Wu, Wen-Bin Yang, Cheng-Wei Cheng, Xiaorui Chen, Ting-Hung Chou, Jiun-Jie Shie, Wei-Chieh Cheng, Rong-Jie Chein, Shi-Shan Mao, Pi-Hui Liang, Che Ma, Shang-Cheng Hung, and Chi-Huey Wong

PNAS February 2, 2021 118 (5) e2021579118; https://doi.org/10.1073/pnas.2021579118
Open Access
Small-molecule endoplasmic reticulum proteostasis regulator acts as a broad-spectrum inhibitor of dengue and Zika virus infections
Katherine M. Almasy, Jonathan P. Davies, Samantha M. Lisy, Reyhaneh Tirgar, Sirena C. Tran, and Lars Plate

PNAS January 19, 2021 118 (3) e2012209118; https://doi.org/10.1073/pnas.2012209118
Open Access
Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target
Łukasz F. Sobala, Pearl Z. Fernandes, Zalihe Hakki, Andrew J. Thompson, Jonathon D. Howe, Michelle Hill, Nicole Zitzmann, Scott Davies, Zania Stamataki, Terry D. Butters, Dominic S. Alonzi, Spencer J. Williams, and Gideon J. Davies

PNAS November 24, 2020 117 (47) 29595-29601; first published November 5, 2020. https://doi.org/10.1073/pnas.2013620117
Open Access
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
Emmie de Wit, Friederike Feldmann, Jacqueline Cronin, Robert Jordan, Atsushi Okumura, Tina Thomas, Dana Scott, Tomas Cihlar, and Heinz Feldmann

PNAS March 24, 2020 117 (12) 6771-6776; first published February 13, 2020. https://doi.org/10.1073/pnas.1922083117
Open Access
Circadian control of interferon-sensitive gene expression in murine skin
Elyse Noelani Greenberg, Michaela Ellen Marshall, Suoqin Jin, Sanan Venkatesh, Morgan Dragan, Lam C. Tsoi, Johann E. Gudjonsson, Qing Nie, Joseph S. Takahashi, and Bogi Andersen

PNAS March 17, 2020 117 (11) 5761-5771; first published March 4, 2020. https://doi.org/10.1073/pnas.1915773117
Open Access
A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo
Evelyn M. Covés-Datson, Steven R. King, Maureen Legendre, Auroni Gupta, Susana M. Chan, Emily Gitlin, Vikram V. Kulkarni, Jezreel Pantaleón García, Donald F. Smee, Elke Lipka, Scott E. Evans, E. Bart Tarbet, Akira Ono, and David M. Markovitz

PNAS January 28, 2020 117 (4) 2122-2132; first published January 13, 2020. https://doi.org/10.1073/pnas.1915152117
Open Access
The mechanism of resistance to favipiravir in influenza
Daniel H. Goldhill, Aartjan J. W. te Velthuis, Robert A. Fletcher, Pinky Langat, Maria Zambon, Angie Lackenby, and Wendy S. Barclay

PNAS November 6, 2018 115 (45) 11613-11618; first published October 23, 2018. https://doi.org/10.1073/pnas.1811345115
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Quantifying antiviral activity optimizes drug combinations against hepatitis C virus infection
Yoshiki Koizumi, Hirofumi Ohashi, Syo Nakajima, Yasuhito Tanaka, Takaji Wakita, Alan S. Perelson, Shingo Iwami, and Koichi Watashi

PNAS February 21, 2017 114 (8) 1922-1927; first published February 7, 2017. https://doi.org/10.1073/pnas.1610197114
See companion article:
HCV entry inhibitors for boosting DAA treatments
- May 16, 2017
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Spironolactone blocks Epstein–Barr virus production by inhibiting EBV SM protein function
Dinesh Verma, Jacob Thompson, and Sankar Swaminathan

PNAS March 29, 2016 113 (13) 3609-3614; first published March 14, 2016. https://doi.org/10.1073/pnas.1523686113
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Bispecific antibodies directed to CD4 domain 2 and HIV envelope exhibit exceptional breadth and picomolar potency against HIV-1
Craig S. Pace, Ruijiang Song, Christina Ochsenbauer, Chasity D. Andrews, David Franco, Jian Yu, Deena A. Oren, Michael S. Seaman, and David D. Ho

PNAS August 13, 2013 110 (33) 13540-13545; https://doi.org/10.1073/pnas.1304985110

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