New Research In

bone

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Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight
- From the Cover
Se-Jin Lee, Adam Lehar, Jessica U. Meir, Christina Koch, Andrew Morgan, Lara E. Warren, Renata Rydzik, Daniel W. Youngstrom, Harshpreet Chandok, Joshy George, Joseph Gogain, Michael Michaud, Thomas A. Stoklasek, Yewei Liu, and Emily L. Germain-Lee

PNAS September 22, 2020 117 (38) 23942-23951; first published September 8, 2020. https://doi.org/10.1073/pnas.2014716117
Open Access
Ontogeny of the anuran urostyle and the developmental context of evolutionary novelty
- From the Cover
Gayani Senevirathne, Stephanie Baumgart, Nathaniel Shubin, James Hanken, and Neil H. Shubin

PNAS February 11, 2020 117 (6) 3034-3044; first published January 27, 2020. https://doi.org/10.1073/pnas.1917506117
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Frogs give new insights into vertebrate novelties
- Feb 05, 2020
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Bone-inspired microarchitectures achieve enhanced fatigue life
Ashley M. Torres, Adwait A. Trikanad, Cameron A. Aubin, Floor M. Lambers, Marysol Luna, Clare M. Rimnac, Pablo Zavattieri, and Christopher J. Hernandez

PNAS December 3, 2019 116 (49) 24457-24462; first published November 18, 2019. https://doi.org/10.1073/pnas.1905814116
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Reply to Zadpoor: Fatigue mechanisms observed in bone provide insight to microarchitectured materials
- Mar 03, 2020
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The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage
Qian Zhang, Ryan C. Riddle, Qian Yang, Clifford R. Rosen, Denis C. Guttridge, Naomi Dirckx, Marie-Claude Faugere, Charles R. Farber, and Thomas L. Clemens

PNAS September 3, 2019 116 (36) 17980-17989; first published August 21, 2019. https://doi.org/10.1073/pnas.1905489116
Open Access
Schwann cell precursors contribute to skeletal formation during embryonic development in mice and zebrafish
- From the Cover
Meng Xie, Dmitrii Kamenev, Marketa Kaucka, Maria Eleni Kastriti, Baoyi Zhou, Artem V. Artemov, Mekayla Storer, Kaj Fried, Igor Adameyko, Vyacheslav Dyachuk, and Andrei S. Chagin

PNAS July 23, 2019 116 (30) 15068-15073; first published July 8, 2019. https://doi.org/10.1073/pnas.1900038116
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Biomaterials-aided mandibular reconstruction using in vivo bioreactors
Alexander M. Tatara, Gerry L. Koons, Emma Watson, Trenton C. Piepergerdes, Sarita R. Shah, Brandon T. Smith, Jonathan Shum, James C. Melville, Issa A. Hanna, Nagi Demian, Tang Ho, Anthony Ratcliffe, Jeroen J. J. P. van den Beucken, John A. Jansen, Mark E. Wong, and Antonios G. Mikos

PNAS April 2, 2019 116 (14) 6954-6963; first published March 18, 2019. https://doi.org/10.1073/pnas.1819246116
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Phosphate graphene as an intrinsically osteoinductive scaffold for stem cell-driven bone regeneration
Anne M. Arnold, Brian D. Holt, Leila Daneshmandi, Cato T. Laurencin, and Stefanie A. Sydlik

PNAS March 12, 2019 116 (11) 4855-4860; first published February 22, 2019. https://doi.org/10.1073/pnas.1815434116
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FAM210A is a novel determinant of bone and muscle structure and strength
Ken-ichiro Tanaka, Yingben Xue, Loan Nguyen-Yamamoto, John A. Morris, Ippei Kanazawa, Toshitsugu Sugimoto, Simon S. Wing, J. Brent Richards, and David Goltzman

PNAS April 17, 2018 115 (16) E3759-E3768; first published April 4, 2018. https://doi.org/10.1073/pnas.1719089115
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HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice
Claire-Sophie Devignes, Yetki Aslan, Audrey Brenot, Audrey Devillers, Koen Schepers, Stéphanie Fabre, Jonathan Chou, Amy-Jo Casbon, Zena Werb, and Sylvain Provot

PNAS January 30, 2018 115 (5) E992-E1001; first published January 16, 2018. https://doi.org/10.1073/pnas.1718009115
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Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes
Soohyun P. Kim, Julie L. Frey, Zhu Li, Priyanka Kushwaha, Meredith L. Zoch, Ryan E. Tomlinson, Hao Da, Susan Aja, Hye Lim Noh, Jason K. Kim, Mehboob A. Hussain, Daniel L. J. Thorek, Michael J. Wolfgang, and Ryan C. Riddle

PNAS December 26, 2017 114 (52) E11238-E11247; first published December 11, 2017. https://doi.org/10.1073/pnas.1707876115

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