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Caenorhabditis elegans

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Metformin rescues Parkinson’s disease phenotypes caused by hyperactive mitochondria
Danielle E. Mor, Salman Sohrabi, Rachel Kaletsky, William Keyes, Alp Tartici, Vrinda Kalia, Gary W. Miller, and Coleen T. Murphy

PNAS October 20, 2020 117 (42) 26438-26447; first published October 6, 2020. https://doi.org/10.1073/pnas.2009838117
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Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation
- From the Cover
Troy A. McDiarmid, Manuel Belmadani, Joseph Liang, Fabian Meili, Eleanor A. Mathews, Gregory P. Mullen, Ardalan Hendi, Wan-Rong Wong, James B. Rand, Kota Mizumoto, Kurt Haas, Paul Pavlidis, and Catharine H. Rankin

PNAS January 7, 2020 117 (1) 656-667; first published November 21, 2019. https://doi.org/10.1073/pnas.1912049116
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Functional testing of ASD-associated genes
- Dec 10, 2019
Open Access
Swim exercise in Caenorhabditis elegans extends neuromuscular and gut healthspan, enhances learning ability, and protects against neurodegeneration
Ricardo Laranjeiro, Girish Harinath, Jennifer E. Hewitt, Jessica H. Hartman, Mary Anne Royal, Joel N. Meyer, Siva A. Vanapalli, and Monica Driscoll

PNAS November 19, 2019 116 (47) 23829-23839; first published November 4, 2019. https://doi.org/10.1073/pnas.1909210116
Open Access
The genomic basis of Red Queen dynamics during rapid reciprocal host–pathogen coevolution
Andrei Papkou, Thiago Guzella, Wentao Yang, Svenja Koepper, Barbara Pees, Rebecca Schalkowski, Mike-Christoph Barg, Philip C. Rosenstiel, Henrique Teotónio, and Hinrich Schulenburg

PNAS January 15, 2019 116 (3) 923-928; first published December 31, 2018. https://doi.org/10.1073/pnas.1810402116
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Endoribonuclease ENDU-2 regulates multiple traits including cold tolerance via cell autonomous and nonautonomous controls in Caenorhabditis elegans
Tomoyo Ujisawa, Akane Ohta, Tatsuya Ii, Yohei Minakuchi, Atsushi Toyoda, Miki Ii, and Atsushi Kuhara

PNAS August 28, 2018 115 (35) 8823-8828; first published August 13, 2018. https://doi.org/10.1073/pnas.1808634115
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Distinct gating mechanism of SOC channel involving STIM–Orai coupling and an intramolecular interaction of Orai in Caenorhabditis elegans
Kyu Min Kim, Tharaka Wijerathne, Jin-Hoe Hur, Uk Jung Kang, Ihn Hyeong Kim, Yeong Cheon Kweon, Ah Reum Lee, Su Ji Jeong, Sang Kwon Lee, Yoon Young Lee, Bo-Woong Sim, Jong-Hee Lee, Chunggi Baig, Sun-Uk Kim, Kyu-Tae Chang, Kyu Pil Lee, and Chan Young Park

PNAS May 15, 2018 115 (20) E4623-E4632; first published April 30, 2018. https://doi.org/10.1073/pnas.1714986115
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Split cGAL, an intersectional strategy using a split intein for refined spatiotemporal transgene control in Caenorhabditis elegans
Han Wang, Jonathan Liu, Kai P. Yuet, Andrew J. Hill, and Paul W. Sternberg

PNAS April 10, 2018 115 (15) 3900-3905; first published March 26, 2018. https://doi.org/10.1073/pnas.1720063115
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Antagonistic regulation of trafficking to Caenorhabditis elegans sensory cilia by a Retinal Degeneration 3 homolog and retromer
Luis A. Martínez-Velázquez and Niels Ringstad

PNAS January 16, 2018 115 (3) E438-E447; first published December 27, 2017. https://doi.org/10.1073/pnas.1712302115
Open Access
Phosphatidylserine save-me signals drive functional recovery of severed axons in Caenorhabditis elegans
Zehra C. Abay, Michelle Yu-Ying Wong, Jean-Sébastien Teoh, Tarika Vijayaraghavan, Massimo A. Hilliard, and Brent Neumann

PNAS November 21, 2017 114 (47) E10196-E10205; first published November 6, 2017. https://doi.org/10.1073/pnas.1703807114
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Axonal fusion in functional recovery
- Nov 06, 2017
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Cell size and fat content of dietary-restricted Caenorhabditis elegans are regulated by ATX-2, an mTOR repressor
Daniel Z. Bar, Chayki Charar, Jehudith Dorfman, Tam Yadid, Lionel Tafforeau, Denis L. J. Lafontaine, and Yosef Gruenbaum

PNAS August 9, 2016 113 (32) E4620-E4629; first published July 25, 2016. https://doi.org/10.1073/pnas.1512156113

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