New Research In

cancer

Open Access
Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds
Abimael Cruz-Migoni, Peter Canning, Camilo E. Quevedo, Carole J. R. Bataille, Nicolas Bery, Ami Miller, Angela J. Russell, Simon E. V. Phillips, Stephen B. Carr, and Terence H. Rabbitts

PNAS February 12, 2019 116 (7) 2545-2550; published ahead of print February 12, 2019. https://doi.org/10.1073/pnas.1811360116
Open Access
Quantitative zeptomolar imaging of miRNA cancer markers with nanoparticle assemblies
Aihua Qu, Maozhong Sun, Liguang Xu, Changlong Hao, Xiaoling Wu, Chuanlai Xu, Nicholas A. Kotov, and Hua Kuang

PNAS published ahead of print February 11, 2019. https://doi.org/10.1073/pnas.1810764116
Open Access
Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperone protein, has broad oncogenic properties
Davide Zella, Sabrina Curreli, Francesca Benedetti, Selvi Krishnan, Fiorenza Cocchi, Olga S. Latinovic, Frank Denaro, Fabio Romerio, Mahmoud Djavani, Man E. Charurat, Joseph L. Bryant, Hervé Tettelin, and Robert C. Gallo

PNAS December 18, 2018 115 (51) E12005-E12014; published ahead of print December 3, 2018. https://doi.org/10.1073/pnas.1815660115
Open Access
ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses
- Inaugural Article
Maria Tokuyama, Yong Kong, Eric Song, Teshika Jayewickreme, Insoo Kang, and Akiko Iwasaki

PNAS December 11, 2018 115 (50) 12565-12572; published ahead of print November 19, 2018. https://doi.org/10.1073/pnas.1814589115
Open Access
Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory
Sophie Viaud, Jennifer S. Y. Ma, Ian R. Hardy, Eric N. Hampton, Brent Benish, Lance Sherwood, Vanessa Nunez, Christopher J. Ackerman, Elvira Khialeeva, Meredith Weglarz, Sung Chang Lee, Ashley K. Woods, and Travis S. Young

PNAS November 13, 2018 115 (46) E10898-E10906; published ahead of print October 29, 2018. https://doi.org/10.1073/pnas.1810060115
Open Access
A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability
Jessica B. A. Sadler, Dawn M. Wenzel, Lauren K. Williams, Marta Guindo-Martínez, Steven L. Alam, Josep M. Mercader, David Torrents, Katharine S. Ullman, Wesley I. Sundquist, and Juan Martin-Serrano

PNAS September 18, 2018 115 (38) E8900-E8908; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1805504115
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Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples
Bizhu Chu, An He, Yeteng Tian, Wan He, Peizhong Chen, Jintao Hu, Ruilian Xu, Wenbin Zhou, Mingjie Zhang, Pengyuan Yang, Shawn S. C. Li, Ying Sun, Pengfei Li, Tony Hunter, and Ruijun Tian

PNAS September 18, 2018 115 (38) E8863-E8872; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1805633115
Open Access
Circular DNA tumor viruses make circular RNAs
Tuna Toptan, Bizunesh Abere, Michael A. Nalesnik, Steven H. Swerdlow, Sarangarajan Ranganathan, Nara Lee, Kathy H. Shair, Patrick S. Moore, and Yuan Chang

PNAS September 11, 2018 115 (37) E8737-E8745; published ahead of print August 27, 2018. https://doi.org/10.1073/pnas.1811728115
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Mutations in the Drosophila tricellular junction protein M6 synergize with Ras^V12 to induce apical cell delamination and invasion
Brandon S. Dunn, Lindsay Rush, Jin-Yu Lu, and Tian Xu

PNAS August 14, 2018 115 (33) 8358-8363; published ahead of print July 30, 2018. https://doi.org/10.1073/pnas.1807343115
Open Access
p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells
Hidekazu Nagano, Naoko Hashimoto, Akitoshi Nakayama, Sawako Suzuki, Yui Miyabayashi, Azusa Yamato, Seiichiro Higuchi, Masanori Fujimoto, Ikki Sakuma, Minako Beppu, Masataka Yokoyama, Yutaka Suzuki, Sumio Sugano, Kazuhiro Ikeda, Ichiro Tatsuno, Ichiro Manabe, Koutaro Yokote, Satoshi Inoue, and Tomoaki Tanaka

PNAS August 14, 2018 115 (33) 8370-8375; published ahead of print July 30, 2018. https://doi.org/10.1073/pnas.1804243115

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