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cancer metastasis

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Transcriptional suppression of AMPKα1 promotes breast cancer metastasis upon oncogene activation
Yong Yi, Deshi Chen, Juan Ao, Wenhua Zhang, Jianqiao Yi, Xiaokun Ren, Junjie Fei, Fengtian Li, Mengmeng Niu, Hu Chen, Yangkun Luo, Zhijun Luo, and Zhi-Xiong Jim Xiao

PNAS April 7, 2020 117 (14) 8013-8021; first published March 19, 2020. https://doi.org/10.1073/pnas.1914786117
Open Access
Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction
Gaofeng Xiong, Jie Chen, Guoying Zhang, Shike Wang, Kunito Kawasaki, Jieqing Zhu, Yan Zhang, Kazuhiro Nagata, Zhenyu Li, Binhua P. Zhou, and Ren Xu

PNAS February 18, 2020 117 (7) 3748-3758; first published February 3, 2020. https://doi.org/10.1073/pnas.1911951117
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Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis
Linjie Zhao, Shuang Huang, Shenglin Mei, Zhengnan Yang, Lian Xu, Nianxin Zhou, Qilian Yang, Qiuhong Shen, Wei Wang, Xiaobing Le, Wayne Bond Lau, Bonnie Lau, Xin Wang, Tao Yi, Xia Zhao, Yuquan Wei, Margaret Warner, Jan-Åke Gustafsson, and Shengtao Zhou

PNAS April 17, 2018 115 (16) E3673-E3681; first published March 28, 2018. https://doi.org/10.1073/pnas.1803291115
Open Access
ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis
Linshan Hu, Shan Liang, Hu Chen, Tao Lv, Junfeng Wu, Deshi Chen, Min Wu, Shengnan Sun, Haibo Zhang, Han You, Hongbin Ji, Yujun Zhang, Johann Bergholz, and Zhi-Xiong Jim Xiao

PNAS May 16, 2017 114 (20) E3964-E3973; first published May 3, 2017. https://doi.org/10.1073/pnas.1617816114
Open Access
Clusters of circulating tumor cells traverse capillary-sized vessels
Sam H. Au, Brian D. Storey, John C. Moore, Qin Tang, Yeng-Long Chen, Sarah Javaid, A. Fatih Sarioglu, Ryan Sullivan, Marissa W. Madden, Ryan O’Keefe, Daniel A. Haber, Shyamala Maheswaran, David M. Langenau, Shannon L. Stott, and Mehmet Toner

PNAS May 3, 2016 113 (18) 4947-4952; first published April 18, 2016. https://doi.org/10.1073/pnas.1524448113
Open Access
Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells
Takashi Nojiri, Hiroshi Hosoda, Takeshi Tokudome, Koichi Miura, Shin Ishikane, Kentaro Otani, Ichiro Kishimoto, Yasushi Shintani, Masayoshi Inoue, Toru Kimura, Noriyoshi Sawabata, Masato Minami, Tomoyuki Nakagiri, Soichiro Funaki, Yukiyasu Takeuchi, Hajime Maeda, Hiroyasu Kidoya, Hiroshi Kiyonari, Go Shioi, Yuji Arai, Takeshi Hasegawa, Nobuyuki Takakura, Megumi Hori, Yuko Ohno, Mikiya Miyazato, Naoki Mochizuki, Meinoshin Okumura, and Kenji Kangawa

PNAS March 31, 2015 112 (13) 4086-4091; first published March 16, 2015. https://doi.org/10.1073/pnas.1417273112
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NanoFlares for the detection, isolation, and culture of live tumor cells from human blood
Tiffany L. Halo, Kaylin M. McMahon, Nicholas L. Angeloni, Yilin Xu, Wei Wang, Alyssa B. Chinen, Dmitry Malin, Elena Strekalova, Vincent L. Cryns, Chonghui Cheng, Chad A. Mirkin, and C. Shad Thaxton

PNAS December 2, 2014 111 (48) 17104-17109; first published November 17, 2014. https://doi.org/10.1073/pnas.1418637111
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The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer
Julius Semenas, Andreas Hedblom, Regina R. Miftakhova, Martuza Sarwar, Rikard Larsson, Liliya Shcherbina, Martin E. Johansson, Pirkko Härkönen, Olov Sterner, and Jenny L. Persson

PNAS September 2, 2014 111 (35) E3689-E3698; first published July 28, 2014. https://doi.org/10.1073/pnas.1405801111
See companion article:
PIP5K1A inhibition in prostate cancer
- Aug 12, 2014
Open Access
Circulating giant macrophages as a potential biomarker of solid tumors
Daniel L. Adams, Stuart S. Martin, R. Katherine Alpaugh, Monica Charpentier, Susan Tsai, Raymond C. Bergan, Irene M. Ogden, William Catalona, Saranya Chumsri, Cha-Mei Tang, and Massimo Cristofanilli

PNAS March 4, 2014 111 (9) 3514-3519; https://doi.org/10.1073/pnas.1320198111
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Blockade of A_2A receptors potently suppresses the metastasis of CD73⁺ tumors
Paul A. Beavis, Upulie Divisekera, Christophe Paget, Melvyn T. Chow, Liza B. John, Christel Devaud, Karen Dwyer, John Stagg, Mark J. Smyth, and Phillip K. Darcy

PNAS September 3, 2013 110 (36) 14711-14716; https://doi.org/10.1073/pnas.1308209110

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