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cell death

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A unique mode of keratinocyte death requires intracellular acidification
Takeshi Matsui, Nanako Kadono-Maekubo, Yoshiro Suzuki, Yuki Furuichi, Keiichiro Shiraga, Hiroyuki Sasaki, Azusa Ishida, Sonoko Takahashi, Takaharu Okada, Kiminori Toyooka, Jafar Sharif, Takaya Abe, Hiroshi Kiyonari, Makoto Tominaga, Atsushi Miyawaki, and Masayuki Amagai

PNAS April 27, 2021 118 (17) e2020722118; https://doi.org/10.1073/pnas.2020722118
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Functional cell death, corneoptosis, requires temporally controlled intracellular acidification
- May 13, 2021
Open Access
Monitoring tumor cell death in murine tumor models using deuterium magnetic resonance spectroscopy and spectroscopic imaging
Friederike Hesse, Vencel Somai, Felix Kreis, Flaviu Bulat, Alan J. Wright, and Kevin M. Brindle

PNAS March 23, 2021 118 (12) e2014631118; https://doi.org/10.1073/pnas.2014631118
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Novel function of N-acetyltransferase for microtubule stability and JNK signaling in Drosophila organ development
Jung-Wan Mok and Kwang-Wook Choi

PNAS January 26, 2021 118 (4) e2010140118; https://doi.org/10.1073/pnas.2010140118
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REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks
Nimrat Chatterjee, Matthew A. Whitman, Cynthia A. Harris, Sophia M. Min, Oliver Jonas, Evan C. Lien, Alba Luengo, Matthew G. Vander Heiden, Jiyong Hong, Pei Zhou, Michael T. Hemann, and Graham C. Walker

PNAS November 17, 2020 117 (46) 28918-28921; first published November 9, 2020. https://doi.org/10.1073/pnas.2016064117
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Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer
- Nov 03, 2020
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The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli
Jacqueline Grimm, Handuo Shi, Wei Wang, Angela M. Mitchell, Ned S. Wingreen, Kerwyn Casey Huang, and Thomas J. Silhavy

PNAS October 27, 2020 117 (43) 26907-26914; first published October 12, 2020. https://doi.org/10.1073/pnas.2015556117
Open Access
Loss of the common immune coreceptor BAK1 leads to NLR-dependent cell death
Yujun Wu, Yang Gao, Yanyan Zhan, Hong Kui, Hongyan Liu, Li Yan, Birgit Kemmerling, Jian-Min Zhou, Kai He, and Jia Li

PNAS October 27, 2020 117 (43) 27044-27053; first published October 14, 2020. https://doi.org/10.1073/pnas.1915339117
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Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy
Jiaming Xue, Simone Patergnani, Carlotta Giorgi, Joelle Suarez, Keisuke Goto, Angela Bononi, Mika Tanji, Flavia Novelli, Sandra Pastorino, Ronghui Xu, Natascia Caroccia, A. Umran Dogan, Harvey I. Pass, Mauro Tognon, Paolo Pinton, Giovanni Gaudino, Tak W. Mak, Michele Carbone, and Haining Yang

PNAS October 13, 2020 117 (41) 25543-25552; first published September 30, 2020. https://doi.org/10.1073/pnas.2007622117
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Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression
Anna Fishbein, Weicang Wang, Haixia Yang, Jun Yang, Victoria M. Hallisey, Jianjun Deng, Sanne M. L. Verheul, Sung Hee Hwang, Allison Gartung, Yuxin Wang, Diane R. Bielenberg, Sui Huang, Mark W. Kieran, Bruce D. Hammock, and Dipak Panigrahy

PNAS September 1, 2020 117 (35) 21576-21587; first published August 14, 2020. https://doi.org/10.1073/pnas.2007412117
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Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects
Vicky Hakim-Eshed, Ayub Boulos, Chen Cohen-Rosenzweig, Libo Yu-Taeger, Tamar Ziv, Yong Tae Kwon, Olaf Riess, Hoa Huu Phuc Nguyen, Noam E. Ziv, and Aaron Ciechanover

PNAS August 4, 2020 117 (31) 18661-18669; first published July 16, 2020. https://doi.org/10.1073/pnas.2007667117
Open Access
Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor
Alice Fletcher-Etherington, Luis Nobre, Katie Nightingale, Robin Antrobus, Jenna Nichols, Andrew J. Davison, Richard J. Stanton, and Michael P. Weekes

PNAS August 4, 2020 117 (31) 18771-18779; first published July 20, 2020. https://doi.org/10.1073/pnas.2001887117

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