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diagnostics

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Direct single-molecule imaging for diagnostic and blood screening assays
Qiaoqiao Ruan, Patrick J. Macdonald, Kerry M. Swift, and Sergey Y. Tetin

PNAS April 6, 2021 118 (14) e2025033118; https://doi.org/10.1073/pnas.2025033118
Open Access
Wireless, soft electronics for rapid, multisensor measurements of hydration levels in healthy and diseased skin
- From the Cover
Kyeongha Kwon, Heling Wang, Jaeman Lim, Keum San Chun, Hokyung Jang, Injae Yoo, Derek Wu, Alyssa Jie Chen, Carol Ge Gu, Lindsay Lipschultz, Jong Uk Kim, Jihye Kim, Hyoyoung Jeong, Haiwen Luan, Yoonseok Park, Chun-Ju Su, Yui Ishida, Surabhi R. Madhvapathy, Akihiko Ikoma, Jean Won Kwak, Da Som Yang, Anthony Banks, Shuai Xu, Yonggang Huang, Jan-Kai Chang, and John A. Rogers

PNAS February 2, 2021 118 (5) e2020398118; https://doi.org/10.1073/pnas.2020398118
Open Access
Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria
- From the Cover
Rose A. Lee, Helena De Puig, Peter Q. Nguyen, Nicolaas M. Angenent-Mari, Nina M. Donghia, James P. McGee, Jeffrey D. Dvorin, Catherine M. Klapperich, Nira R. Pollock, and James J. Collins

PNAS October 13, 2020 117 (41) 25722-25731; first published September 21, 2020. https://doi.org/10.1073/pnas.2010196117
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Tunable and precise miniature lithium heater for point-of-care applications
Buddhisha Udugama, Pranav Kadhiresan, and Warren C. W. Chan

PNAS March 3, 2020 117 (9) 4632-4641; first published February 18, 2020. https://doi.org/10.1073/pnas.1916562117
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High-throughput assessment of hemoglobin polymer in single red blood cells from sickle cell patients under controlled oxygen tension
Giuseppe Di Caprio, Ethan Schonbrun, Bronner P. Gonçalves, Jose M. Valdez, David K. Wood, and John M. Higgins

PNAS December 10, 2019 116 (50) 25236-25242; first published November 25, 2019. https://doi.org/10.1073/pnas.1914056116
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Ultrasensitive, multiplexed chemoproteomic profiling with soluble activity-dependent proximity ligation
Gang Li, Mark A. Eckert, Jae Won Chang, Jeffrey E. Montgomery, Agnieszka Chryplewicz, Ernst Lengyel, and Raymond E. Moellering

PNAS October 22, 2019 116 (43) 21493-21500; first published October 7, 2019. https://doi.org/10.1073/pnas.1912934116
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Digital-resolution detection of microRNA with single-base selectivity by photonic resonator absorption microscopy
Taylor D. Canady, Nantao Li, Lucas D. Smith, Yi Lu, Manish Kohli, Andrew M. Smith, and Brian T. Cunningham

PNAS September 24, 2019 116 (39) 19362-19367; first published September 9, 2019. https://doi.org/10.1073/pnas.1904770116
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Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing
Hui Li, Peter Torab, Kathleen E. Mach, Christine Surrette, Matthew R. England, David W. Craft, Neal J. Thomas, Joseph C. Liao, Chris Puleo, and Pak Kin Wong

PNAS May 21, 2019 116 (21) 10270-10279; first published May 8, 2019. https://doi.org/10.1073/pnas.1819569116
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Multiplex targeted mass spectrometry assay for one-shot flavivirus diagnosis
Sheena Wee, Asfa Alli-Shaik, Relus Kek, Hannah L. F. Swa, Wei-Ping Tien, Vanessa W. Lim, Yee-Sin Leo, Lee-Ching Ng, Hapuarachchige C. Hapuarachchi, and Jayantha Gunaratne

PNAS April 2, 2019 116 (14) 6754-6759; first published March 18, 2019. https://doi.org/10.1073/pnas.1817867116
Open Access
Volatile biomarkers of symptomatic and asymptomatic malaria infection in humans
Consuelo M. De Moraes, Caroline Wanjiku, Nina M. Stanczyk, Hannier Pulido, James W. Sims, Heike S. Betz, Andrew F. Read, Baldwyn Torto, and Mark C. Mescher

PNAS May 29, 2018 115 (22) 5780-5785; first published May 14, 2018. https://doi.org/10.1073/pnas.1801512115

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