New Research In

DNA binding

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Interaction between p53 N terminus and core domain regulates specific and nonspecific DNA binding
Fan He, Wade Borcherds, Tanjing Song, Xi Wei, Mousumi Das, Lihong Chen, Gary W. Daughdrill, and Jiandong Chen

PNAS April 30, 2019 116 (18) 8859-8868; first published April 15, 2019. https://doi.org/10.1073/pnas.1903077116
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Intermediate step of cohesin’s ATPase cycle allows cohesin to entrap DNA
Gamze Ö. Çamdere, Kristian K. Carlborg, and Douglas Koshland

PNAS September 25, 2018 115 (39) 9732-9737; first published September 10, 2018. https://doi.org/10.1073/pnas.1807213115
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MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis
Qingling Huang, Lihong Chen, Leixiang Yang, Xiaoling Xie, Lin Gan, John L. Cleveland, and Jiandong Chen

PNAS April 10, 2018 115 (15) E3368-E3377; first published March 26, 2018. https://doi.org/10.1073/pnas.1719090115
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Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS
Litao Sun, Youngzee Song, David Blocquel, Xiang-Lei Yang, and Paul Schimmel

PNAS December 13, 2016 113 (50) 14300-14305; first published November 28, 2016. https://doi.org/10.1073/pnas.1617316113
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Mammalian Period represses and de-represses transcription by displacing CLOCK–BMAL1 from promoters in a Cryptochrome-dependent manner
Yi-Ying Chiou, Yanyan Yang, Naim Rashid, Rui Ye, Christopher P. Selby, and Aziz Sancar

PNAS October 11, 2016 113 (41) E6072-E6079; first published September 29, 2016. https://doi.org/10.1073/pnas.1612917113
See companion article:
Human genome cisplatin damage and repair maps
- Sep 29, 2016
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Secondary interaction between MDMX and p53 core domain inhibits p53 DNA binding
Xi Wei, Shaofang Wu, Tanjing Song, Lihong Chen, Ming Gao, Wade Borcherds, Gary W. Daughdrill, and Jiandong Chen

PNAS May 10, 2016 113 (19) E2558-E2563; first published April 25, 2016. https://doi.org/10.1073/pnas.1603838113
Open Access
Structure and mechanism of the phage T4 recombination mediator protein UvsY
Stefan Gajewski, Michael Brett Waddell, Sivaraja Vaithiyalingam, Amanda Nourse, Zhenmei Li, Nils Woetzel, Nathan Alexander, Jens Meiler, and Stephen W. White

PNAS March 22, 2016 113 (12) 3275-3280; first published March 7, 2016. https://doi.org/10.1073/pnas.1519154113
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Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA
Vera Alverdi, Byron Hetrick, Simpson Joseph, and Elizabeth A. Komives

PNAS January 7, 2014 111 (1) 225-230; first published December 23, 2013. https://doi.org/10.1073/pnas.1318115111
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p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation
- Inaugural Article
Oleg Laptenko, Rachel Beckerman, Ella Freulich, and Carol Prives

PNAS June 28, 2011 108 (26) 10385-10390; https://doi.org/10.1073/pnas.1105680108
Open Access
Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis
Yu-Ming Chang, Wen-Yih Jeng, Tzu-Ping Ko, Yao-Jen Yeh, Cammy K.-M. Chen, and Andrew H.-J. Wang

PNAS May 11, 2010 107 (19) 8617-8622; https://doi.org/10.1073/pnas.0913302107

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