New Research In

drug target

You have access
Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication
Kendra E. Leigh, Mayuri Sharma, My Sam Mansueto, Andras Boeszoermenyi, David J. Filman, James M. Hogle, Gerhard Wagner, Donald M. Coen, and Haribabu Arthanari

PNAS July 21, 2015 112 (29) 9010-9015; first published July 6, 2015. https://doi.org/10.1073/pnas.1511140112
You have access
Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s disease
Chun-Hyung Kim, Baek-Soo Han, Jisook Moon, Deog-Joong Kim, Joon Shin, Sreekanth Rajan, Quoc Toan Nguyen, Mijin Sohn, Won-Gon Kim, Minjoon Han, Inhye Jeong, Kyoung-Shim Kim, Eun-Hye Lee, Yupeng Tu, Jacqueline L. Naffin-Olivos, Chang-Hwan Park, Dagmar Ringe, Ho Sup Yoon, Gregory A. Petsko, and Kwang-Soo Kim

PNAS July 14, 2015 112 (28) 8756-8761; first published June 29, 2015. https://doi.org/10.1073/pnas.1509742112
You have access
Structure of the trypanosome cyanide-insensitive alternative oxidase
Tomoo Shiba, Yasutoshi Kido, Kimitoshi Sakamoto, Daniel Ken Inaoka, Chiaki Tsuge, Ryoko Tatsumi, Gen Takahashi, Emmanuel Oluwadare Balogun, Takeshi Nara, Takashi Aoki, Teruki Honma, Akiko Tanaka, Masayuki Inoue, Shigeru Matsuoka, Hiroyuki Saimoto, Anthony L. Moore, Shigeharu Harada, and Kiyoshi Kita

PNAS March 19, 2013 110 (12) 4580-4585; https://doi.org/10.1073/pnas.1218386110
Open Access
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Yongyuth Yuthavong, Bongkoch Tarnchompoo, Tirayut Vilaivan, Penchit Chitnumsub, Sumalee Kamchonwongpaisan, Susan A. Charman, Danielle N. McLennan, Karen L. White, Livia Vivas, Emily Bongard, Chawanee Thongphanchang, Supannee Taweechai, Jarunee Vanichtanankul, Roonglawan Rattanajak, Uthai Arwon, Pascal Fantauzzi, Jirundon Yuvaniyama, William N. Charman, and David Matthews

PNAS October 16, 2012 109 (42) 16823-16828; https://doi.org/10.1073/pnas.1204556109
Open Access
Pathway and mechanism of drug binding to G-protein-coupled receptors
Ron O. Dror, Albert C. Pan, Daniel H. Arlow, David W. Borhani, Paul Maragakis, Yibing Shan, Huafeng Xu, and David E. Shaw

PNAS August 9, 2011 108 (32) 13118-13123; first published July 21, 2011. https://doi.org/10.1073/pnas.1104614108
You have access
Critical role of a K⁺ channel in Plasmodium berghei transmission revealed by targeted gene disruption
Peter Ellekvist, Jorge Maciel, Godfree Mlambo, Christina H. Ricke, Hanne Colding, Dan A. Klaerke, and Nirbhay Kumar

PNAS April 29, 2008 105 (17) 6398-6402; first published April 23, 2008. https://doi.org/10.1073/pnas.0802384105

Main menu

User menu

Search

New Research In

drug target

Articles

PNAS Portals

Information

Main menu

User menu

Search

New Research In

Physical Sciences

Featured Portals

Articles by Topic

Social Sciences

Featured Portals

Articles by Topic

Biological Sciences

Featured Portals

Articles by Topic

drug target

Articles

PNAS Portals

Information