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HSP70

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Local translation in nuclear condensate amyloid bodies
Phaedra R. Theodoridis, Michael Bokros, Dane Marijan, Nathan C. Balukoff, Dazhi Wang, Chloe C. Kirk, Taylor D. Budine, Harris D. Goldsmith, Miling Wang, Timothy E. Audas, and Stephen Lee

PNAS February 16, 2021 118 (7) e2014457118; https://doi.org/10.1073/pnas.2014457118
Open Access
Kinetics of the conformational cycle of Hsp70 reveals the importance of the dynamic and heterogeneous nature of Hsp70 for its function
Si Wu, Liu Hong, Yuqing Wang, Jieqiong Yu, Jie Yang, Jie Yang, Hong Zhang, and Sarah Perrett

PNAS April 7, 2020 117 (14) 7814-7823; first published March 20, 2020. https://doi.org/10.1073/pnas.1914376117
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Necroptosis-blocking compound NBC1 targets heat shock protein 70 to inhibit MLKL polymerization and necroptosis
Andrea N. Johnston, Yuyong Ma, Hua Liu, Shuzhen Liu, Sarah Hanna-Addams, She Chen, Chuo Chen, and Zhigao Wang

PNAS March 24, 2020 117 (12) 6521-6530; first published March 10, 2020. https://doi.org/10.1073/pnas.1916503117
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The Hsp70 chaperone is a major player in stress-induced transposable element activation
- From the Cover
Ugo Cappucci, Fabrizia Noro, Assunta Maria Casale, Laura Fanti, Maria Berloco, Angela Alessandra Alagia, Luigi Grassi, Loredana Le Pera, Lucia Piacentini, and Sergio Pimpinelli

PNAS September 3, 2019 116 (36) 17943-17950; first published August 9, 2019. https://doi.org/10.1073/pnas.1903936116
See companion article:
Stress: An evolutionary mutagen
- Aug 21, 2019
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Allosteric landscapes of eukaryotic cytoplasmic Hsp70s are shaped by evolutionary tuning of key interfaces
Wenli Meng, Eugenia M. Clerico, Natalie McArthur, and Lila M. Gierasch

PNAS November 20, 2018 115 (47) 11970-11975; first published November 5, 2018. https://doi.org/10.1073/pnas.1811105115
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Arthropod EVs mediate dengue virus transmission through interaction with a tetraspanin domain containing glycoprotein Tsp29Fb
Ashish Vora, Wenshuo Zhou, Berlin Londono-Renteria, Michael Woodson, Michael B. Sherman, Tonya M. Colpitts, Girish Neelakanta, and Hameeda Sultana

PNAS July 10, 2018 115 (28) E6604-E6613; first published June 26, 2018. https://doi.org/10.1073/pnas.1720125115
Open Access
Chaperone AMPylation modulates aggregation and toxicity of neurodegenerative disease-associated polypeptides
Matthias C. Truttmann, David Pincus, and Hidde L. Ploegh

PNAS May 29, 2018 115 (22) E5008-E5017; first published May 14, 2018. https://doi.org/10.1073/pnas.1801989115
Open Access
Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response
Matthias C. Truttmann, Xu Zheng, Leo Hanke, Jadyn R. Damon, Monique Grootveld, Joanna Krakowiak, David Pincus, and Hidde L. Ploegh

PNAS January 10, 2017 114 (2) E152-E160; first published December 28, 2016. https://doi.org/10.1073/pnas.1619234114
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Holdase activity of secreted Hsp70 masks amyloid-β42 neurotoxicity in Drosophila
Pedro Fernandez-Funez, Jonatan Sanchez-Garcia, Lorena de Mena, Yan Zhang, Yona Levites, Swati Khare, Todd E. Golde, and Diego E. Rincon-Limas

PNAS August 30, 2016 113 (35) E5212-E5221; first published August 16, 2016. https://doi.org/10.1073/pnas.1608045113
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Combined chemical–genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma
Amit J. Sabnis, Christopher J. Guerriero, Victor Olivas, Anin Sayana, Jonathan Shue, Jennifer Flanagan, Saurabh Asthana, Adrienne W. Paton, James C. Paton, Jason E. Gestwicki, Peter Walter, Jonathan S. Weissman, Peter Wipf, Jeffrey L. Brodsky, and Trever G. Bivona

PNAS August 9, 2016 113 (32) 9015-9020; first published July 22, 2016. https://doi.org/10.1073/pnas.1603883113

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