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infection

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FXR mediates T cell-intrinsic responses to reduced feeding during infection
Clarissa Campbell, Francois Marchildon, Anthony J. Michaels, Naofumi Takemoto, Joris van der Veeken, Michail Schizas, Yuri Pritykin, Christina S. Leslie, Andrew M. Intlekofer, Paul Cohen, and Alexander Y. Rudensky

PNAS December 29, 2020 117 (52) 33446-33454; first published December 14, 2020. https://doi.org/10.1073/pnas.2020619117
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Reston virus causes severe respiratory disease in young domestic pigs
Elaine Haddock, Greg Saturday, Friederike Feldmann, Patrick W. Hanley, Atsushi Okumura, Jamie Lovaglio, Dan Long, Tina Thomas, Dana P. Scott, Mikayla Pulliam, Jürgen A. Richt, Emmie de Wit, and Heinz Feldmann

PNAS January 12, 2021 118 (2) e2015657118; https://doi.org/10.1073/pnas.2015657118
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Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population
J. Justin Milner, Hongtuyet Nguyen, Kyla Omilusik, Miguel Reina-Campos, Matthew Tsai, Clara Toma, Arnaud Delpoux, Brigid S. Boland, Stephen M. Hedrick, John T. Chang, and Ananda W. Goldrath

PNAS October 13, 2020 117 (41) 25667-25678; first published September 25, 2020. https://doi.org/10.1073/pnas.2008571117
Open Access
Overweight, obesity, and risk of hospitalization for COVID-19: A community-based cohort study of adults in the United Kingdom
Mark Hamer, Catharine R. Gale, Mika Kivimäki, and G. David Batty

PNAS September 1, 2020 117 (35) 21011-21013; first published August 11, 2020. https://doi.org/10.1073/pnas.2011086117
Open Access
Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development
Masaki Imai, Kiyoko Iwatsuki-Horimoto, Masato Hatta, Samantha Loeber, Peter J. Halfmann, Noriko Nakajima, Tokiko Watanabe, Michiko Ujie, Kenta Takahashi, Mutsumi Ito, Shinya Yamada, Shufang Fan, Shiho Chiba, Makoto Kuroda, Lizheng Guan, Kosuke Takada, Tammy Armbrust, Aaron Balogh, Yuri Furusawa, Moe Okuda, Hiroshi Ueki, Atsuhiro Yasuhara, Yuko Sakai-Tagawa, Tiago J. S. Lopes, Maki Kiso, Seiya Yamayoshi, Noriko Kinoshita, Norio Ohmagari, Shin-ichiro Hattori, Makoto Takeda, Hiroaki Mitsuya, Florian Krammer, Tadaki Suzuki, and Yoshihiro Kawaoka

PNAS July 14, 2020 117 (28) 16587-16595; first published June 22, 2020. https://doi.org/10.1073/pnas.2009799117
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Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues
Chun-Liang Chen, S. Saif Hasan, Thomas Klose, Yingyuan Sun, Geeta Buda, Chengqun Sun, William B. Klimstra, and Michael G. Rossmann

PNAS April 21, 2020 117 (16) 8890-8899; first published April 3, 2020. https://doi.org/10.1073/pnas.1910670117
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Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease
Steven J. Mileto, Thierry Jardé, Kevin O. Childress, Jaime L. Jensen, Ashleigh P. Rogers, Genevieve Kerr, Melanie L. Hutton, Michael J. Sheedlo, Sarah C. Bloch, John A. Shupe, Katja Horvay, Tracey Flores, Rebekah Engel, Simon Wilkins, Paul J. McMurrick, D. Borden Lacy, Helen E. Abud, and Dena Lyras

PNAS April 7, 2020 117 (14) 8064-8073; first published March 20, 2020. https://doi.org/10.1073/pnas.1915255117
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Facilitative and synergistic interactions between fungal and plant viruses
Ruiling Bian, Ida Bagus Andika, Tianxing Pang, Ziqian Lian, Shuang Wei, Erbo Niu, Yunfeng Wu, Hideki Kondo, Xili Liu, and Liying Sun

PNAS February 18, 2020 117 (7) 3779-3788; first published February 3, 2020. https://doi.org/10.1073/pnas.1915996117
Open Access
Robust hepatitis E virus infection and transcriptional response in human hepatocytes
Daniel Todt, Martina Friesland, Nora Moeller, Dimas Praditya, Volker Kinast, Yannick Brüggemann, Leonard Knegendorf, Thomas Burkard, Joerg Steinmann, Rani Burm, Lieven Verhoye, Avista Wahid, Toni Luise Meister, Michael Engelmann, Vanessa M. Pfankuche, Christina Puff, Florian W. R. Vondran, Wolfgang Baumgärtner, Philip Meuleman, Patrick Behrendt, and Eike Steinmann

PNAS January 21, 2020 117 (3) 1731-1741; first published January 2, 2020. https://doi.org/10.1073/pnas.1912307117
Open Access
ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection
Jayna J. Mistry, Christopher R. Marlein, Jamie A. Moore, Charlotte Hellmich, Edyta E. Wojtowicz, James G. W. Smith, Iain Macaulay, Yu Sun, Adam Morfakis, Angela Patterson, Rebecca H. Horton, Devina Divekar, Christopher J. Morris, Anna Haestier, Federica Di Palma, Naiara Beraza, Kristian M. Bowles, and Stuart A. Rushworth

PNAS December 3, 2019 116 (49) 24610-24619; first published November 14, 2019. https://doi.org/10.1073/pnas.1913278116

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