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infection

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Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues
Chun-Liang Chen, S. Saif Hasan, Thomas Klose, Yingyuan Sun, Geeta Buda, Chengqun Sun, William B. Klimstra, and Michael G. Rossmann

PNAS April 21, 2020 117 (16) 8890-8899; first published April 3, 2020. https://doi.org/10.1073/pnas.1910670117
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Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease
Steven J. Mileto, Thierry Jardé, Kevin O. Childress, Jaime L. Jensen, Ashleigh P. Rogers, Genevieve Kerr, Melanie L. Hutton, Michael J. Sheedlo, Sarah C. Bloch, John A. Shupe, Katja Horvay, Tracey Flores, Rebekah Engel, Simon Wilkins, Paul J. McMurrick, D. Borden Lacy, Helen E. Abud, and Dena Lyras

PNAS April 7, 2020 117 (14) 8064-8073; first published March 20, 2020. https://doi.org/10.1073/pnas.1915255117
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Facilitative and synergistic interactions between fungal and plant viruses
Ruiling Bian, Ida Bagus Andika, Tianxing Pang, Ziqian Lian, Shuang Wei, Erbo Niu, Yunfeng Wu, Hideki Kondo, Xili Liu, and Liying Sun

PNAS February 18, 2020 117 (7) 3779-3788; first published February 3, 2020. https://doi.org/10.1073/pnas.1915996117
Open Access
Robust hepatitis E virus infection and transcriptional response in human hepatocytes
Daniel Todt, Martina Friesland, Nora Moeller, Dimas Praditya, Volker Kinast, Yannick Brüggemann, Leonard Knegendorf, Thomas Burkard, Joerg Steinmann, Rani Burm, Lieven Verhoye, Avista Wahid, Toni Luise Meister, Michael Engelmann, Vanessa M. Pfankuche, Christina Puff, Florian W. R. Vondran, Wolfgang Baumgärtner, Philip Meuleman, Patrick Behrendt, and Eike Steinmann

PNAS January 21, 2020 117 (3) 1731-1741; first published January 2, 2020. https://doi.org/10.1073/pnas.1912307117
Open Access
ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection
Jayna J. Mistry, Christopher R. Marlein, Jamie A. Moore, Charlotte Hellmich, Edyta E. Wojtowicz, James G. W. Smith, Iain Macaulay, Yu Sun, Adam Morfakis, Angela Patterson, Rebecca H. Horton, Devina Divekar, Christopher J. Morris, Anna Haestier, Federica Di Palma, Naiara Beraza, Kristian M. Bowles, and Stuart A. Rushworth

PNAS December 3, 2019 116 (49) 24610-24619; first published November 14, 2019. https://doi.org/10.1073/pnas.1913278116
Open Access
Molecular basis for retinol binding by serum amyloid A during infection
Zehan Hu, Ye-Ji Bang, Kelly A. Ruhn, and Lora V. Hooper

PNAS September 17, 2019 116 (38) 19077-19082; first published September 4, 2019. https://doi.org/10.1073/pnas.1910713116
Open Access
Resistance in marine cyanobacteria differs against specialist and generalist cyanophages
Sophia Zborowsky and Debbie Lindell

PNAS August 20, 2019 116 (34) 16899-16908; first published August 5, 2019. https://doi.org/10.1073/pnas.1906897116
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The purine biosynthesis regulator PurR moonlights as a virulence regulator in Staphylococcus aureus
William E. Sause, Divya Balasubramanian, Irnov Irnov, Richard Copin, Mitchell J. Sullivan, Alexis Sommerfield, Rita Chan, Avantika Dhabaria, Manor Askenazi, Beatrix Ueberheide, Bo Shopsin, Harm van Bakel, and Victor J. Torres

PNAS July 2, 2019 116 (27) 13563-13572; first published June 19, 2019. https://doi.org/10.1073/pnas.1904280116
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Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing
Hui Li, Peter Torab, Kathleen E. Mach, Christine Surrette, Matthew R. England, David W. Craft, Neal J. Thomas, Joseph C. Liao, Chris Puleo, and Pak Kin Wong

PNAS May 21, 2019 116 (21) 10270-10279; first published May 8, 2019. https://doi.org/10.1073/pnas.1819569116
Open Access
Renal control of disease tolerance to malaria
Susana Ramos, Ana Rita Carlos, Balamurugan Sundaram, Viktoria Jeney, Ana Ribeiro, Raffaella Gozzelino, Claudia Bank, Erida Gjini, Faouzi Braza, Rui Martins, Temitope Wilson Ademolue, Birte Blankenhaus, Zélia Gouveia, Pedro Faísca, Damian Trujillo, Sílvia Cardoso, Sofia Rebelo, Laura del Barrio, Abolfazl Zarjou, Subhashini Bolisetty, Anupam Agarwal, and Miguel P. Soares

PNAS March 19, 2019 116 (12) 5681-5686; first published March 4, 2019. https://doi.org/10.1073/pnas.1822024116

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