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lung

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Fluorescent reconstitution on deposition of PM_2.5 in lung and extrapulmonary organs
Donghai Li, Yongjian Li, Guiling Li, Yu Zhang, Jiang Li, and Haosheng Chen

PNAS February 12, 2019 116 (7) 2488-2493; first published February 12, 2019. https://doi.org/10.1073/pnas.1818134116
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In vivo imaging of the pathophysiological changes and neutrophil dynamics in influenza virus-infected mouse lungs
Hiroshi Ueki, I-Hsuan Wang, Satoshi Fukuyama, Hiroaki Katsura, Tiago Jose da Silva Lopes, Gabriele Neumann, and Yoshihiro Kawaoka

PNAS July 10, 2018 115 (28) E6622-E6629; first published June 25, 2018. https://doi.org/10.1073/pnas.1806265115
Open Access
Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling
Suifang Mao, Alok S. Shah, Thomas O. Moninger, Lynda S. Ostedgaard, Lin Lu, Xiao Xiao Tang, Ian M. Thornell, Leah R. Reznikov, Sarah E. Ernst, Philip H. Karp, Ping Tan, Shaf Keshavjee, Mahmoud H. Abou Alaiwa, and Michael J. Welsh

PNAS February 6, 2018 115 (6) 1370-1375; first published January 22, 2018. https://doi.org/10.1073/pnas.1719177115
Open Access
Gel-forming mucins form distinct morphologic structures in airways
Lynda S. Ostedgaard, Thomas O. Moninger, James D. McMenimen, Nicholas M. Sawin, Connor P. Parker, Ian M. Thornell, Linda S. Powers, Nicholas D. Gansemer, Drake C. Bouzek, Daniel P. Cook, David K. Meyerholz, Mahmoud H. Abou Alaiwa, David A. Stoltz, and Michael J. Welsh

PNAS June 27, 2017 114 (26) 6842-6847; first published June 12, 2017. https://doi.org/10.1073/pnas.1703228114
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Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma
Arvin M. Gouw, Livia S. Eberlin, Katherine Margulis, Delaney K. Sullivan, Georgia G. Toal, Ling Tong, Richard N. Zare, and Dean W. Felsher

PNAS April 25, 2017 114 (17) 4300-4305; first published April 11, 2017. https://doi.org/10.1073/pnas.1617709114
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Preclinical efficacy of a RAF inhibitor that evades paradoxical MAPK pathway activation in protein kinase BRAF-mutant lung cancer
Ross A. Okimoto, Luping Lin, Victor Olivas, Elton Chan, Evan Markegard, Andrey Rymar, Dana Neel, Xiao Chen, Golzar Hemmati, Gideon Bollag, and Trever G. Bivona

PNAS November 22, 2016 113 (47) 13456-13461; first published November 9, 2016. https://doi.org/10.1073/pnas.1610456113
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Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma
Heather E. Metz, Julia Kargl, Stephanie E. Busch, Kyoung-Hee Kim, Brenda F. Kurland, Shira R. Abberbock, Julie Randolph-Habecker, Sue E. Knoblaugh, Jay K. Kolls, Morris F. White, and A. McGarry Houghton

PNAS August 2, 2016 113 (31) 8795-8800; first published July 20, 2016. https://doi.org/10.1073/pnas.1601989113
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Leukotriene E₄ elicits respiratory epithelial cell mucin release through the G-protein–coupled receptor, GPR99
Lora G. Bankova, Juying Lai, Eri Yoshimoto, Joshua A. Boyce, K. Frank Austen, Yoshihide Kanaoka, and Nora A. Barrett

PNAS May 31, 2016 113 (22) 6242-6247; first published May 16, 2016. https://doi.org/10.1073/pnas.1605957113
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Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling
Gani Oruqaj, Srikanth Karnati, Vijith Vijayan, Lakshmi Kanth Kotarkonda, Eistine Boateng, Wenming Zhang, Clemens Ruppert, Andreas Günther, Wei Shi, and Eveline Baumgart-Vogt

PNAS April 21, 2015 112 (16) E2048-E2057; first published April 6, 2015. https://doi.org/10.1073/pnas.1415111112
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Fibroblasts secrete Slit2 to inhibit fibrocyte differentiation and fibrosis
Darrell Pilling, Zhichao Zheng, Varsha Vakil, and Richard H. Gomer

PNAS December 23, 2014 111 (51) 18291-18296; first published December 8, 2014. https://doi.org/10.1073/pnas.1417426112

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