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myosin

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Optimized filopodia formation requires myosin tail domain cooperation
Ashley L. Arthur, Livia D. Songster, Helena Sirkia, Akash Bhattacharya, Carlos Kikuti, Fernanda Pires Borrega, Anne Houdusse, and Margaret A. Titus

PNAS October 29, 2019 116 (44) 22196-22204; first published October 14, 2019. https://doi.org/10.1073/pnas.1901527116
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Structural basis for power stroke vs. Brownian ratchet mechanisms of motor proteins
Wonmuk Hwang and Martin Karplus

PNAS October 1, 2019 116 (40) 19777-19785; first published September 10, 2019. https://doi.org/10.1073/pnas.1818589116
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Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner
- From the Cover
Hannah S. Picariello, Rajappa S. Kenchappa, Vandana Rai, James F. Crish, Athanassios Dovas, Katarzyna Pogoda, Mariah McMahon, Emily S. Bell, Unnikrishnan Chandrasekharan, Amanda Luu, Rita West, Jan Lammerding, Peter Canoll, David J. Odde, Paul A. Janmey, Thomas Egelhoff, and Steven S. Rosenfeld

PNAS July 30, 2019 116 (31) 15550-15559; first published June 24, 2019. https://doi.org/10.1073/pnas.1902847116
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Meddling with myosin’s mechanobiology in cancer
- Jul 11, 2019
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Active cargo positioning in antiparallel transport networks
Mathieu Richard, Carles Blanch-Mercader, Hajer Ennomani, Wenxiang Cao, Enrique M. De La Cruz, Jean-François Joanny, Frank Jülicher, Laurent Blanchoin, and Pascal Martin

PNAS July 23, 2019 116 (30) 14835-14842; first published July 9, 2019. https://doi.org/10.1073/pnas.1900416116
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Myosin Va transport of liposomes in three-dimensional actin networks is modulated by actin filament density, position, and polarity
- From the Cover
Andrew T. Lombardo, Shane R. Nelson, Guy G. Kennedy, Kathleen M. Trybus, Sam Walcott, and David M. Warshaw

PNAS April 23, 2019 116 (17) 8326-8335; first published April 9, 2019. https://doi.org/10.1073/pnas.1901176116
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Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA from Toxoplasma gondii
Cameron J. Powell, Raghavendran Ramaswamy, Anne Kelsen, David J. Hamelin, David M. Warshaw, Jürgen Bosch, John E. Burke, Gary E. Ward, and Martin J. Boulanger

PNAS November 6, 2018 115 (45) E10548-E10555; first published October 22, 2018. https://doi.org/10.1073/pnas.1811167115
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Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers
Robert L. Anderson, Darshan V. Trivedi, Saswata S. Sarkar, Marcus Henze, Weikang Ma, Henry Gong, Christopher S. Rogers, Joshua M. Gorham, Fiona L. Wong, Makenna M. Morck, Jonathan G. Seidman, Kathleen M. Ruppel, Thomas C. Irving, Roger Cooke, Eric M. Green, and James A. Spudich

PNAS August 28, 2018 115 (35) E8143-E8152; first published August 13, 2018. https://doi.org/10.1073/pnas.1809540115
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Mavacamten stabilizes an autoinhibited state of two-headed cardiac myosin
- Jul 17, 2018
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Drosophila model of myosin myopathy rescued by overexpression of a TRIM-protein family member
Martin Dahl-Halvarsson, Montse Olive, Malgorzata Pokrzywa, Katarina Ejeskär, Ruth H. Palmer, Anne Elisabeth Uv, and Homa Tajsharghi

PNAS July 10, 2018 115 (28) E6566-E6575; first published June 26, 2018. https://doi.org/10.1073/pnas.1800727115
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An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics
Florian Blanc, Tatiana Isabet, Hannah Benisty, H. Lee Sweeney, Marco Cecchini, and Anne Houdusse

PNAS June 12, 2018 115 (24) 6213-6218; first published May 29, 2018. https://doi.org/10.1073/pnas.1711512115
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Filament rigidity and connectivity tune the deformation modes of active biopolymer networks
Samantha Stam, Simon L. Freedman, Shiladitya Banerjee, Kimberly L. Weirich, Aaron R. Dinner, and Margaret L. Gardel

PNAS November 21, 2017 114 (47) E10037-E10045; first published November 7, 2017. https://doi.org/10.1073/pnas.1708625114

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