New Research In

natural killer cells

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Synaptic secretion from human natural killer cells is diverse and includes supramolecular attack particles
Ashley R. Ambrose, Khodor S. Hazime, Jonathan D. Worboys, Olatz Niembro-Vivanco, and Daniel M. Davis

PNAS September 22, 2020 117 (38) 23717-23720; first published September 8, 2020. https://doi.org/10.1073/pnas.2010274117
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The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function
Philippa M. Saunders, Bruce J. MacLachlan, Phillip Pymm, Patricia T. Illing, Yuanchen Deng, Shu Cheng Wong, Clare V. L. Oates, Anthony W. Purcell, Jamie Rossjohn, Julian P. Vivian, and Andrew G. Brooks

PNAS May 26, 2020 117 (21) 11636-11647; first published May 13, 2020. https://doi.org/10.1073/pnas.1920570117
Open Access
Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation
Leah Schmidt, Banu Eskiocak, Ryan Kohn, Celeste Dang, Nikhil S. Joshi, Michel DuPage, Da-Yae Lee, and Tyler Jacks

PNAS August 27, 2019 116 (35) 17460-17469; first published August 13, 2019. https://doi.org/10.1073/pnas.1904253116
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Critical role for the Ly49 family of class I MHC receptors in adaptive natural killer cell responses
- From the Cover
Andrew Wight, Ahmad Bakur Mahmoud, Michal Scur, Megan M. Tu, Mir Munir A. Rahim, Subash Sad, and Andrew P. Makrigiannis

PNAS November 6, 2018 115 (45) 11579-11584; first published September 24, 2018. https://doi.org/10.1073/pnas.1722374115
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Natural killer cells might adapt their inhibitory receptors for memory
- Oct 18, 2018
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Siglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cells
Jerry J. Fong, Chih-Ming Tsai, Sudeshna Saha, Victor Nizet, Ajit Varki, and Jack D. Bui

PNAS October 9, 2018 115 (41) 10410-10415; first published September 25, 2018. https://doi.org/10.1073/pnas.1804108115
Open Access
Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT
Tim D. Holmes, Erica B. Wilson, Emma V. I. Black, Andrew V. Benest, Candida Vaz, Betty Tan, Vivek M. Tanavde, and Graham P. Cook

PNAS December 30, 2014 111 (52) E5688-E5696; first published December 15, 2014. https://doi.org/10.1073/pnas.1411072112
Open Access
Behçet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity
- From the Cover
Michael J. Ombrello, Yohei Kirino, Paul I. W. de Bakker, Ahmet Gül, Daniel L. Kastner, and Elaine F. Remmers

PNAS June 17, 2014 111 (24) 8867-8872; first published May 12, 2014. https://doi.org/10.1073/pnas.1406575111
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HLA-B*51 is the primary risk in Behçet disease
- May 29, 2014
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Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A
Emily M. Mace and Jordan S. Orange

PNAS May 6, 2014 111 (18) 6708-6713; first published April 23, 2014. https://doi.org/10.1073/pnas.1314975111
Open Access
Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist
Lyudmila G. Burdelya, Craig M. Brackett, Bojidar Kojouharov, Ilya I. Gitlin, Katerina I. Leonova, Anatoli S. Gleiberman, Semra Aygun-Sunar, Jean Veith, Christopher Johnson, Gary J. Haderski, Patricia Stanhope-Baker, Shyam Allamaneni, Joseph Skitzki, Ming Zeng, Elena Martsen, Alexander Medvedev, Dmitry Scheblyakov, Nataliya M. Artemicheva, Denis Y. Logunov, Alexander L. Gintsburg, Boris S. Naroditsky, Sergei S. Makarov, and Andrei V. Gudkov

PNAS May 14, 2013 110 (20) E1857-E1866; https://doi.org/10.1073/pnas.1222805110

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