New Research In

natural killer cells

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Hobit confers tissue-dependent programs to type 1 innate lymphoid cells
Kentaro Yomogida, Tarin M. Bigley, Tihana Trsan, Susan Gilfillan, Marina Cella, Wayne M. Yokoyama, Takeshi Egawa, and Marco Colonna

PNAS December 14, 2021 118 (50) e2117965118; https://doi.org/10.1073/pnas.2117965118
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Multispecific targeting of glioblastoma with tumor microenvironment-responsive multifunctional engineered NK cells
Jiao Wang, Sandra Toregrosa-Allen, Bennett D. Elzey, Sagar Utturkar, Nadia Atallah Lanman, Victor Bernal-Crespo, Matthew M. Behymer, Gregory T. Knipp, Yeonhee Yun, Michael C. Veronesi, Anthony L. Sinn, Karen E. Pollok, Randy R. Brutkiewicz, Kathryn S. Nevel, and Sandro Matosevic

PNAS November 9, 2021 118 (45) e2107507118; https://doi.org/10.1073/pnas.2107507118
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A functional mammalian display screen identifies rare antibodies that stimulate NK cell–mediated cytotoxicity
Emily Kang, Cigall Kadoch, James L. Rubenstein, Lewis L. Lanier, and James A. Wells

PNAS August 3, 2021 118 (31) e2104099118; https://doi.org/10.1073/pnas.2104099118
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Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment
Uriel Y. Moreno-Nieves, Joshua K. Tay, Saumyaa Saumyaa, Nina B. Horowitz, June Ho Shin, Imran A. Mohammad, Bogdan Luca, David C. Mundy, Gunsagar S. Gulati, Nikita Bedi, Serena Chang, Chen Chen, Michael J. Kaplan, Eben L. Rosenthal, F. Christopher Holsinger, Vasu Divi, Fred M. Baik, Davud B. Sirjani, Andrew J. Gentles, Aaron M. Newman, Aharon G. Freud, and John B. Sunwoo

PNAS July 13, 2021 118 (28) e2101169118; https://doi.org/10.1073/pnas.2101169118
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Intraepithelial ILC1-like cells: Front-line fighters in human head and neck squamous cell carcinoma
- Aug 10, 2021
Open Access
High-dimensional mass cytometry analysis of NK cell alterations in AML identifies a subgroup with adverse clinical outcome
Anne-Sophie Chretien, Raynier Devillier, Samuel Granjeaud, Charlotte Cordier, Clemence Demerle, Nassim Salem, Julia Wlosik, Florence Orlanducci, Laurent Gorvel, Stephane Fattori, Marie-Anne Hospital, Jihane Pakradouni, Emilie Gregori, Magali Paul, Philippe Rochigneux, Thomas Pagliardini, Mathieu Morey, Cyril Fauriat, Nicolas Dulphy, Antoine Toubert, Herve Luche, Marie Malissen, Didier Blaise, Jacques A. Nunès, Norbert Vey, and Daniel Olive

PNAS June 1, 2021 118 (22) e2020459118; https://doi.org/10.1073/pnas.2020459118
Open Access
Synaptic secretion from human natural killer cells is diverse and includes supramolecular attack particles
Ashley R. Ambrose, Khodor S. Hazime, Jonathan D. Worboys, Olatz Niembro-Vivanco, and Daniel M. Davis

PNAS September 22, 2020 117 (38) 23717-23720; first published September 8, 2020. https://doi.org/10.1073/pnas.2010274117
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The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function
Philippa M. Saunders, Bruce J. MacLachlan, Phillip Pymm, Patricia T. Illing, Yuanchen Deng, Shu Cheng Wong, Clare V. L. Oates, Anthony W. Purcell, Jamie Rossjohn, Julian P. Vivian, and Andrew G. Brooks

PNAS May 26, 2020 117 (21) 11636-11647; first published May 13, 2020. https://doi.org/10.1073/pnas.1920570117
Open Access
Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation
Leah Schmidt, Banu Eskiocak, Ryan Kohn, Celeste Dang, Nikhil S. Joshi, Michel DuPage, Da-Yae Lee, and Tyler Jacks

PNAS August 27, 2019 116 (35) 17460-17469; first published August 13, 2019. https://doi.org/10.1073/pnas.1904253116
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Critical role for the Ly49 family of class I MHC receptors in adaptive natural killer cell responses
- From the Cover
Andrew Wight, Ahmad Bakur Mahmoud, Michal Scur, Megan M. Tu, Mir Munir A. Rahim, Subash Sad, and Andrew P. Makrigiannis

PNAS November 6, 2018 115 (45) 11579-11584; first published September 24, 2018. https://doi.org/10.1073/pnas.1722374115
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Natural killer cells might adapt their inhibitory receptors for memory
- Oct 18, 2018
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Siglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cells
Jerry J. Fong, Chih-Ming Tsai, Sudeshna Saha, Victor Nizet, Ajit Varki, and Jack D. Bui

PNAS October 9, 2018 115 (41) 10410-10415; first published September 25, 2018. https://doi.org/10.1073/pnas.1804108115

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