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sex differences

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The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients
Sarah Pyfrom, Bam Paneru, James J. Knox, Michael P. Cancro, Sylvia Posso, Jane H. Buckner, and Montserrat C. Anguera

PNAS June 15, 2021 118 (24) e2024624118; https://doi.org/10.1073/pnas.2024624118
Open Access
Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma
Najla Kfoury, Zongtai Qi, Briana C. Prager, Michael N. Wilkinson, Lauren Broestl, Kristopher C. Berrett, Arnav Moudgil, Sumithra Sankararaman, Xuhua Chen, Jason Gertz, Jeremy N. Rich, Robi D. Mitra, and Joshua B. Rubin

PNAS April 20, 2021 118 (16) e2017148118; https://doi.org/10.1073/pnas.2017148118
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Perinatal androgens organize sex differences in mast cells and attenuate anaphylaxis severity into adulthood
Emily Mackey, Kyan M. Thelen, Vedrana Bali, Mahsa Fardisi, Madalyn Trowbridge, Cynthia L. Jordan, and Adam J. Moeser

PNAS September 22, 2020 117 (38) 23751-23761; first published September 11, 2020. https://doi.org/10.1073/pnas.1915075117
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Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans
Siyuan Liu, Jakob Seidlitz, Jonathan D. Blumenthal, Liv S. Clasen, and Armin Raznahan

PNAS August 4, 2020 117 (31) 18788-18798; first published July 20, 2020. https://doi.org/10.1073/pnas.1919091117
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Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism
Sarthak Gupta, Shuichiro Nakabo, Luz P. Blanco, Liam J. O’Neil, Gustaf Wigerblad, Rishi R. Goel, Pragnesh Mistry, Kan Jiang, Carmelo Carmona-Rivera, Diana W. Chan, Xinghao Wang, Hege L. Pedersen, Manasi Gadkari, Katherine N. Howe, Faiza Naz, Stefania Dell’Orso, Sarfaraz A. Hasni, Caeden Dempsey, Ashley Buscetta, Pamela A. Frischmeyer-Guerrerio, Paul Kruszka, Maximilian Muenke, Luis M. Franco, Hong-Wei Sun, and Mariana J. Kaplan

PNAS July 14, 2020 117 (28) 16481-16491; first published June 29, 2020. https://doi.org/10.1073/pnas.2003603117
Open Access
Parent-of-origin differences in DNA methylation of X chromosome genes in T lymphocytes
- From the Cover
Lisa C. Golden, Yuichiro Itoh, Noriko Itoh, Sonia Iyengar, Patrick Coit, Youstina Salama, Arthur P. Arnold, Amr H. Sawalha, and Rhonda R. Voskuhl

PNAS December 26, 2019 116 (52) 26779-26787; first published December 10, 2019. https://doi.org/10.1073/pnas.1910072116
Open Access
Neural substrates of sexual arousal are not sex dependent
Ekaterina Mitricheva, Rui Kimura, Nikos K. Logothetis, and Hamid R. Noori

PNAS July 30, 2019 116 (31) 15671-15676; first published July 15, 2019. https://doi.org/10.1073/pnas.1904975116
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Reply to Poeppl et al.: Controlling for false positive rates is critical for accurate and consistent interpretation of findings
- May 05, 2020
Open Access
Persistent metabolic youth in the aging female brain
Manu S. Goyal, Tyler M. Blazey, Yi Su, Lars E. Couture, Tony J. Durbin, Randall J. Bateman, Tammie L.-S. Benzinger, John C. Morris, Marcus E. Raichle, and Andrei G. Vlassenko

PNAS February 19, 2019 116 (8) 3251-3255; first published February 4, 2019. https://doi.org/10.1073/pnas.1815917116
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Reply to Biskup et al. and Tu et al.: Sex differences in metabolic brain aging
- May 28, 2019
Open Access
Testing the Empathizing–Systemizing theory of sex differences and the Extreme Male Brain theory of autism in half a million people
- From the Cover
David M. Greenberg, Varun Warrier, Carrie Allison, and Simon Baron-Cohen

PNAS November 27, 2018 115 (48) 12152-12157; first published November 12, 2018. https://doi.org/10.1073/pnas.1811032115
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Autism in the broader context of cognitive sex differences
- Nov 12, 2018
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Reply to Perrykkad and Hohwy: When big data are the answer
- Jul 03, 2019
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Sex-chromosome dosage effects on gene expression in humans
Armin Raznahan, Neelroop N. Parikshak, Vijay Chandran, Jonathan D. Blumenthal, Liv S. Clasen, Aaron F. Alexander-Bloch, Andrew R. Zinn, Danny Wangsa, Jasen Wise, Declan G. M. Murphy, Patrick F. Bolton, Thomas Ried, Judith Ross, Jay N. Giedd, and Daniel H. Geschwind

PNAS July 10, 2018 115 (28) 7398-7403; first published June 26, 2018. https://doi.org/10.1073/pnas.1802889115

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