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skin cancer

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Deep phenotyping of 89 xeroderma pigmentosum patients reveals unexpected heterogeneity dependent on the precise molecular defect
Hiva Fassihi, Mieran Sethi, Heather Fawcett, Jonathan Wing, Natalie Chandler, Shehla Mohammed, Emma Craythorne, Ana M. S. Morley, Rongxuan Lim, Sally Turner, Tanya Henshaw, Isabel Garrood, Paola Giunti, Tammy Hedderly, Adesoji Abiona, Harsha Naik, Gemma Harrop, David McGibbon, Nicolaas G. J. Jaspers, Elena Botta, Tiziana Nardo, Miria Stefanini, Antony R. Young, Robert P. E. Sarkany, and Alan R. Lehmann

PNAS March 1, 2016 113 (9) E1236-E1245; first published February 16, 2016. https://doi.org/10.1073/pnas.1519444113
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Label-free DNA imaging in vivo with stimulated Raman scattering microscopy
Fa-Ke Lu, Srinjan Basu, Vivien Igras, Mai P. Hoang, Minbiao Ji, Dan Fu, Gary R. Holtom, Victor A. Neel, Christian W. Freudiger, David E. Fisher, and X. Sunney Xie

PNAS September 15, 2015 112 (37) 11624-11629; first published August 31, 2015. https://doi.org/10.1073/pnas.1515121112
Open Access
Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRas^Q61L)-driven SerpinB2 expression
Linda K. Rushworth, Andrew M. Kidger, Laurent Delavaine, Graeme Stewart, Susanne van Schelven, Jane Davidson, Christopher J. Bryant, Edward Caddye, Philip East, Christopher J. Caunt, and Stephen M. Keyse

PNAS December 23, 2014 111 (51) 18267-18272; first published December 8, 2014. https://doi.org/10.1073/pnas.1420159112
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Regulation of cell proliferation and migration by p62 through stabilization of Twist1
Lei Qiang, Baozhong Zhao, Mei Ming, Ning Wang, Tong-Chuan He, Seungmin Hwang, Andrew Thorburn, and Yu-Ying He

PNAS June 24, 2014 111 (25) 9241-9246; first published June 9, 2014. https://doi.org/10.1073/pnas.1322913111
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MC1R and cAMP signaling inhibit cdc25B activity and delay cell cycle progression in melanoma cells
Jesse Lyons, Boris C. Bastian, and Frank McCormick

PNAS August 20, 2013 110 (34) 13845-13850; https://doi.org/10.1073/pnas.1201917110
Open Access
CD200-expressing human basal cell carcinoma cells initiate tumor growth
Chantal S. Colmont, Antisar BenKetah, Simon H. Reed, Nga V. Hawk, William G. Telford, Manabu Ohyama, Mark C. Udey, Carole L. Yee, Jonathan C. Vogel, and Girish K. Patel

PNAS January 22, 2013 110 (4) 1434-1439; https://doi.org/10.1073/pnas.1211655110
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Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells
Norman Sachs, Pablo Secades, Laura van Hulst, Maaike Kreft, Ji-Ying Song, and Arnoud Sonnenberg

PNAS December 26, 2012 109 (52) 21468-21473; https://doi.org/10.1073/pnas.1204614110
Open Access
Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling
Markus Schober and Elaine Fuchs

PNAS June 28, 2011 108 (26) 10544-10549; https://doi.org/10.1073/pnas.1107807108
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Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r
Elodie Le Pape, Thierry Passeron, Alessio Giubellino, Julio C. Valencia, Rainer Wolber, and Vincent J. Hearing

PNAS February 10, 2009 106 (6) 1802-1807; first published January 27, 2009. https://doi.org/10.1073/pnas.0806753106

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