New Research In

stem cells

Open Access
The effect of parathyroid hormone on osteogenesis is mediated partly by osteolectin
- Inaugural Article
Jingzhu Zhang, Adi Cohen, Bo Shen, Liming Du, Alpaslan Tasdogan, Zhiyu Zhao, Elizabeth J. Shane, and Sean J. Morrison

PNAS June 22, 2021 118 (25) e2026176118; https://doi.org/10.1073/pnas.2026176118
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Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland
Annelies Vennekens, Emma Laporte, Florian Hermans, Benoit Cox, Elodie Modave, Adrian Janiszewski, Charlotte Nys, Hiroto Kobayashi, Bert Malengier-Devlies, Joel Chappell, Patrick Matthys, Marie-Isabelle Garcia, Vincent Pasque, Diether Lambrechts, and Hugo Vankelecom

PNAS June 22, 2021 118 (25) e2100052118; https://doi.org/10.1073/pnas.2100052118
Open Access
A versatile platform for locus-scale genome rewriting and verification
Ran Brosh, Jon M. Laurent, Raquel Ordoñez, Emily Huang, Megan S. Hogan, Angela M. Hitchcock, Leslie A. Mitchell, Sudarshan Pinglay, John A. Cadley, Raven D. Luther, David M. Truong, Jef D. Boeke, and Matthew T. Maurano

PNAS March 9, 2021 118 (10) e2023952118; https://doi.org/10.1073/pnas.2023952118
Open Access
The esophageal gland mediates host immune evasion by the human parasite Schistosoma mansoni
- From the Cover
Jayhun Lee, Tracy Chong, and Phillip A. Newmark

PNAS August 11, 2020 117 (32) 19299-19309; first published July 31, 2020. https://doi.org/10.1073/pnas.2006553117
Open Access
Regulation of ERK basal and pulsatile activity control proliferation and exit from the stem cell compartment in mammalian epidermis
Toru Hiratsuka, Ignacio Bordeu, Gunnar Pruessner, and Fiona M. Watt

PNAS July 28, 2020 117 (30) 17796-17807; first published July 10, 2020. https://doi.org/10.1073/pnas.2006965117
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Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway
Tongguang Wang, Marie Medynets, Kory R. Johnson, Tara T. Doucet-O’Hare, Brianna DiSanza, Wenxue Li, Yadi Xu, Anna Bagnell, Richa Tyagi, Kevon Sampson, Nasir Malik, Joseph Steiner, Alina Hadegan, Jeffrey Kowalak, James O'Malley, Dragan Maric, and Avindra Nath

PNAS July 28, 2020 117 (30) 17842-17853; first published July 15, 2020. https://doi.org/10.1073/pnas.2002427117
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Rocks in the auxin stream: Wound-induced auxin accumulation and ERF115 expression synergistically drive stem cell regeneration
Balkan Canher, Jefri Heyman, Maria Savina, Ajay Devendran, Thomas Eekhout, Ilse Vercauteren, Els Prinsen, Rotem Matosevich, Jian Xu, Victoria Mironova, and Lieven De Veylder

PNAS July 14, 2020 117 (28) 16667-16677; first published June 29, 2020. https://doi.org/10.1073/pnas.2006620117
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Wounding-induced changes in cellular pressure and localized auxin signalling spatially coordinate restorative divisions in roots
- Jun 15, 2020
Open Access
JNK-dependent intestinal barrier failure disrupts host–microbe homeostasis during tumorigenesis
Jun Zhou and Michael Boutros

PNAS April 28, 2020 117 (17) 9401-9412; first published April 10, 2020. https://doi.org/10.1073/pnas.1913976117
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The aging skin microenvironment dictates stem cell behavior
Yejing Ge, Yuxuan Miao, Shiri Gur-Cohen, Nicholas Gomez, Hanseul Yang, Maria Nikolova, Lisa Polak, Yang Hu, Akanksha Verma, Olivier Elemento, James G. Krueger, and Elaine Fuchs

PNAS March 10, 2020 117 (10) 5339-5350; first published February 24, 2020. https://doi.org/10.1073/pnas.1901720117
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Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion
Johan H. van Es, Kay Wiebrands, Carmen López-Iglesias, Marc van de Wetering, Laura Zeinstra, Maaike van den Born, Jeroen Korving, Nobuo Sasaki, Peter J. Peters, Alexander van Oudenaarden, and Hans Clevers

PNAS December 26, 2019 116 (52) 26599-26605; first published December 16, 2019. https://doi.org/10.1073/pnas.1801888117

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