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whole-genome sequencing

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Integrated mutational landscape analysis of uterine leiomyosarcomas
Jungmin Choi, Aranzazu Manzano, Weilai Dong, Stefania Bellone, Elena Bonazzoli, Luca Zammataro, Xiaotong Yao, Aditya Deshpande, Samir Zaidi, Adele Guglielmi, Barbara Gnutti, Nupur Nagarkatti, Joan R. Tymon-Rosario, Justin Harold, Dennis Mauricio, Burak Zeybek, Gulden Menderes, Gary Altwerger, Kyungjo Jeong, Siming Zhao, Natalia Buza, Pei Hui, Antonella Ravaggi, Eliana Bignotti, Chiara Romani, Paola Todeschini, Laura Zanotti, Franco Odicino, Sergio Pecorelli, Laura Ardighieri, Kaya Bilguvar, Charles M. Quick, Dan-Arin Silasi, Gloria S. Huang, Vaagn Andikyan, Mitchell Clark, Elena Ratner, Masoud Azodi, Marcin Imielinski, Peter E. Schwartz, Ludmil B. Alexandrov, Richard P. Lifton, Joseph Schlessinger, and Alessandro D. Santin

PNAS April 13, 2021 118 (15) e2025182118; https://doi.org/10.1073/pnas.2025182118
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A comparative genomics approach identifies contact-dependent growth inhibition as a virulence determinant
Jonathan P. Allen, Egon A. Ozer, George Minasov, Ludmilla Shuvalova, Olga Kiryukhina, Wayne F. Anderson, Karla J. F. Satchell, and Alan R. Hauser

PNAS March 24, 2020 117 (12) 6811-6821; first published March 10, 2020. https://doi.org/10.1073/pnas.1919198117
Open Access
Genetic selection of athletic success in sport-hunting dogs
- From the Cover
Jaemin Kim, Falina J. Williams, Dayna L. Dreger, Jocelyn Plassais, Brian W. Davis, Heidi G. Parker, and Elaine A. Ostrander

PNAS July 24, 2018 115 (30) E7212-E7221; first published July 3, 2018. https://doi.org/10.1073/pnas.1800455115
Open Access
Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa
Ola Brønstad Brynildsrud, Vegard Eldholm, Jon Bohlin, Kennedy Uadiale, Stephen Obaro, and Dominique A. Caugant

PNAS May 22, 2018 115 (21) 5510-5515; first published May 7, 2018. https://doi.org/10.1073/pnas.1802298115
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Haemophilus influenzae genome evolution during persistence in the human airways in chronic obstructive pulmonary disease
Melinda M. Pettigrew, Christian P. Ahearn, Janneane F. Gent, Yong Kong, Mary C. Gallo, James B. Munro, Adonis D’Mello, Sanjay Sethi, Hervé Tettelin, and Timothy F. Murphy

PNAS April 3, 2018 115 (14) E3256-E3265; first published March 19, 2018. https://doi.org/10.1073/pnas.1719654115
Open Access
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis
- Inaugural Article
Xiaopu Zhou, Yu Chen, Kin Y. Mok, Qianhua Zhao, Keliang Chen, Yuewen Chen, John Hardy, Yun Li, Amy K. Y. Fu, Qihao Guo, Nancy Y. Ip, and for the Alzheimer’s Disease Neuroimaging Initiative

PNAS February 20, 2018 115 (8) 1697-1706; first published February 5, 2018. https://doi.org/10.1073/pnas.1715554115
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Profile of Nancy Ip
- Feb 05, 2018
Open Access
Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks
Gustavo C. Cerqueira, Ashlee M. Earl, Christoph M. Ernst, Yonatan H. Grad, John P. Dekker, Michael Feldgarden, Sinéad B. Chapman, João L. Reis-Cunha, Terrance P. Shea, Sarah Young, Qiandong Zeng, Mary L. Delaney, Diane Kim, Ellena M. Peterson, Thomas F. O’Brien, Mary Jane Ferraro, David C. Hooper, Susan S. Huang, James E. Kirby, Andrew B. Onderdonk, Bruce W. Birren, Deborah T. Hung, Lisa A. Cosimi, Jennifer R. Wortman, Cheryl I. Murphy, and William P. Hanage

PNAS January 31, 2017 114 (5) 1135-1140; first published January 17, 2017. https://doi.org/10.1073/pnas.1616248114
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Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans
Vivian S. Lee, Carmen M. Halabi, Erin P. Hoffman, Nikkola Carmichael, Ignaty Leshchiner, Christine G. Lian, Andrew J. Bierhals, Dana Vuzman, Brigham Genomic Medicine, Robert P. Mecham, Natasha Y. Frank, and Nathan O. Stitziel

PNAS August 2, 2016 113 (31) 8759-8764; first published July 18, 2016. https://doi.org/10.1073/pnas.1601442113
Open Access
Population genomics of Mycobacterium tuberculosis in the Inuit
Robyn S. Lee, Nicolas Radomski, Jean-Francois Proulx, Ines Levade, B. Jesse Shapiro, Fiona McIntosh, Hafid Soualhine, Dick Menzies, and Marcel A. Behr

PNAS November 3, 2015 112 (44) 13609-13614; first published October 19, 2015. https://doi.org/10.1073/pnas.1507071112
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Clinical Genomic Database
Benjamin D. Solomon, Anh-Dao Nguyen, Kelly A. Bear, and Tyra G. Wolfsberg

PNAS June 11, 2013 110 (24) 9851-9855; https://doi.org/10.1073/pnas.1302575110

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